Multilayer dressing for assisting wound healing

A protective layer and filling layer technology, applied in the chemical field, can solve problems such as inconvenient use, unbalanced force, and unfit dressings

Pending Publication Date: 2021-09-10
SUZHOU ORIZA MEDICAL INSTR CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these common wet dressings still have certain defects. For example, these common wet dressings are all fixed in shape. Due to the inconsistent shape of the wound, the dressing needs to be manually cut by the user during use, so that the dressing and the wound can be effectively and fully Fitting, which easily leads to the risk of dressing contamination, and is inconvenient to use; these common wet dressings are of fixed thickness, and due to the inconsistency of the wound depth, the dressing cannot fully fit the wound, which leads to unbalanced force and reduces The effect of the dressing; In addition, in the actual treatment of wounds, there are often penetrating wounds caused by external forces, and deep wounds such as fistula tracts and fistulas. There is no matching dressing to use directly, and the wound dressing can only be cut multiple times, and then Filling the wound makes the dressing more difficult to fit the wound, which is extremely inconvenient to use

Method used

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  • Multilayer dressing for assisting wound healing
  • Multilayer dressing for assisting wound healing
  • Multilayer dressing for assisting wound healing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Embodiment 1: A kind of moist dressing and preparation method thereof

[0047] This embodiment provides a wet dressing, the preparation method of which is as follows:

[0048] Mix 0.5mol PPG6000 triol (weight-average molecular weight of 6000) with 2.5mol HDI, react at 80°C for 1 hour to obtain the reaction product; add 0.85mol PEG1000 (weight-average molecular weight of 1000), 0.85mol PEG2000 ( The weight average molecular weight is 2000) and 0.1mol hyaluronic acid (the weight average component is 1,000,000), cross-linking reaction at 80°C for 6 hours to obtain star-shaped hydrophilic polyurethane; 0.1mol sodium bicarbonate (foaming agent), 0.4 mol water, 0.5mol polydimethylsiloxane-polyoxyalkylene copolymer (surfactant), 0.1mol ethylenediamine and 0.1mol zinc isooctanoate (catalyst) are mixed to obtain a foaming component; the star-shaped hydrophilic After the permanent polyurethane and the foaming component were mixed uniformly according to the mass ratio of 1:2.5, t...

Embodiment 2

[0049] Embodiment 2: a kind of moist dressing and preparation method thereof

[0050] This embodiment provides a wet dressing, the preparation method of which is as follows:

[0051] On the basis of Example 1, by 0.1mol sodium bicarbonate (foaming agent), 0.4mol water, 0.5mol polydimethylsiloxane-polyoxyalkylene copolymer (surfactant), 0.1mol ethylenediamine and 0.1mol zinc isooctanoate (catalyst) is mixed and the foaming component is replaced by 0.1mol sodium bicarbonate (foaming agent), 0.4mol water, 0.5mol polydimethylsiloxane-polyoxyalkylene copolymer (interface active agent), 0.1mol ethylenediamine and 0.4mol dimethylethanolamine (catalyst) were mixed to obtain a foaming component, and wet dressing 2 was obtained.

Embodiment 3

[0052] Embodiment 3: a kind of moist dressing and preparation method thereof

[0053] This embodiment provides a wet dressing, the preparation method of which is as follows:

[0054] On the basis of Example 1, by 0.1mol sodium bicarbonate (foaming agent), 0.4mol water, 0.5mol polydimethylsiloxane-polyoxyalkylene copolymer (surfactant), 0.1mol ethylenediamine and 0.1mol of zinc isooctanoate (catalyst) is mixed and the foaming component is replaced by 0.1mol of sodium bicarbonate (foaming agent), 0.4mol of water, 0.5mol of polyoxyalkylene (surfactant), 0.2mol of butanediamine and 0.4 mol dimethylethanolamine (catalyst) was mixed to obtain a foaming component, and wet dressing 3 was obtained.

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Abstract

The invention relates to multilayer dressing for assisting wound healing and belongs to the technical field of chemistry. The invention provides the multilayer dressing. The multilayer dressing comprises a protective layer, a filling layer and a buffer layer located between the protective layer and the filling layer, wherein the filling layer is made of a wet dressing prepared by mixing star-shaped hydrophilic polyurethane with a foaming component and then carrying out foaming. Due to the fact that the wet dressing has certain mechanical strength, can have a certain supporting effect on a wound in a body surface, has free deformability, can achieve comprehensive filling of irregular portions of the wound without dead corners, and the risk of growth of bacteria in the wound is reduces, so that the multilayer dressing provided by the invention has the advantages of being convenient to use, capable of being attached to the wound in a consistent mode, capable of achieving free filling of the wound and capable of accelerating the healing speed of the wound, and is particularly suitable for first-aid perforated wounds and various wounds with fistula tracts and fistulae.

Description

technical field [0001] The invention relates to a multilayer dressing for assisting wound healing, belonging to the technical field of chemistry. Background technique [0002] In 1962, Dr. Winter of the University of London first confirmed with animal experiments (pigs) that the wound healing speed in a wet environment is twice as fast as that in a dry wound. In 1963, Hinman confirmed the scientificity of moist healing with human studies. In August 2000, the U.S. Food and Drug Administration (A) particularly emphasized in the newly promulgated industry guidelines for wound surface medical supplies (external medicines and dressings) that maintaining a moist environment on the wound surface is a standard treatment method. [0003] The advantages of wound healing in a humid environment include: providing a moderately moist environment for the wound, accelerating wound healing, and significantly shortening the treatment time of the wound; the humid environment will not form dry...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F13/02A61L15/18A61L15/24A61L15/26A61L15/28A61L15/40A61L15/42A61M1/00
CPCA61F13/02A61F13/00029A61F13/00068A61L15/26A61L15/24A61L15/18A61L15/40A61L15/42A61L15/28C08L5/08C08L75/04C08L71/02C08L29/04
Inventor 付进停吴鸿
Owner SUZHOU ORIZA MEDICAL INSTR CO LTD
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