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Chloasma-fading composition and preparation method thereof

A composition and a technology for chloasma, applied in the field of medicine, can solve problems such as unsatisfactory treatment effect, and achieve the effect of convenient administration and good effect

Active Publication Date: 2021-10-01
HEBEI YUZHILIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing therapeutic prescriptions are not ideal in terms of therapeutic effect.

Method used

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  • Chloasma-fading composition and preparation method thereof
  • Chloasma-fading composition and preparation method thereof
  • Chloasma-fading composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0034] Preparation Example 1 Preparation of Radix Angelicae Radix Extract

[0035] The preparation method of Angelica dahurica extract is as follows:

[0036] Pulverize the medicinal material of Angelica dahurica, pass through a 10-mesh sieve, add 8 times the amount of 30% ethanol by volume, soak at room temperature for 1 hour, and extract dynamically for 6 hours in countercurrent to obtain the extract;

[0037] After the extract was filtered, it was centrifuged to obtain the supernatant;

[0038] The supernatant was concentrated under reduced pressure to a solid content of 1.35 g / ml to obtain a concentrate;

[0039] The concentrate is belt-dried and the temperature is controlled at 105-110° C. to obtain a dry product, which is pulverized to obtain the Angelica dahurica extract.

Embodiment 1

[0041] A preparation method of a composition for lightening chloasma, comprising the steps of:

[0042] A. Weigh grape seed extract, Angelica sinensis extract, Angelica dahurica extract, Codonopsis pilosula extract, Radix Paeoniae Alba extract, Salvia miltiorrhiza extract, beeswax, pulverize, sieve, then add wheat germ oil, mix, and make capsule core;

[0043] B. Add the capsule core to the capsule material, and press it into soft capsules of 0.5 g each; the preparation method of the capsule material includes: mixing and dissolving the auxiliary materials gelatin, glycerin, and water in a volume ratio of 1:0.6:1.

[0044] C. The soft capsules are washed, dried, screened, inner-packed and outer-packed in turn to make a finished product.

Embodiment 2

[0046]A preparation method of a composition for lightening chloasma, comprising the steps of:

[0047] A. Weigh grape seed extract, Angelica sinensis extract, Angelica dahurica extract, Codonopsis pilosula extract, Radix Paeoniae Alba extract, Salvia miltiorrhiza extract, beeswax, pulverize, sieve, then add wheat germ oil, mix, and make capsule core;

[0048] B. Add the capsule core to the capsule material, and press it into soft capsules of 0.4 g each; the preparation method of the capsule material includes: mixing and dissolving the auxiliary materials gelatin, glycerin, and water in a volume ratio of 1:0.4:1.

[0049] C. The soft capsules are washed, dried, screened, inner-packed and outer-packed in turn to make a finished product.

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Abstract

The invention relates to a chloasma-fading composition and a preparation method thereof. Specifically, the composition is prepared from the following raw materials in parts by weight: 20-60 parts of a grape seed extract, 20-70 parts of an angelica sinensis extract, 20-70 parts of an angelica dahurica extract, 20-70 parts of a codonopsis pilosula extract, 20-70 parts of a radix paeoniae alba extract and 20-70 parts of a salvia miltiorrhiza extract. According to the traditional Chinese medicine pill, the selected medicinal materials are appropriate in compatibility, the traditional Chinese medicine and modern medicine research theories are met, all the medicinal materials are combined, the functions of soothing the liver, relieving depression, tonifying qi, activating blood and removing freckles are achieved, and the traditional Chinese medicine pill is good in liver depression and qi stagnation type chloasma treatment effect, convenient to take, safe and effective.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a composition for lightening chloasma and a preparation method thereof. Background technique [0002] Chloasma, which is called "liver spot, dark spot, and butterfly spot" in traditional Chinese medicine, has been recorded as early as in the "Internal Classics". Its face is as black as lacquered wood." "Lingshu·Evil Qi Viscera and Disease Forms" also said: "Twelve meridians, three hundred and sixty-five collaterals, the qi and blood all go up the face and go through the aperture." Explain the five internal organs and six internal organs The essence of the essence is all injected on the face. The quality of the facial complexion, the luster or withering of the skin, and the formation of pigment spots are closely related to the ups and downs of viscera and the coordination of their functions. [0003] It can be seen that ancient physicians have a unified understanding of chloas...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/87A61K9/48A61K47/44A61P17/00A61K35/644
CPCA61K36/87A61K36/232A61K36/344A61K36/71A61K36/65A61K36/537A61K9/4858A61K9/4825A61P17/00A61K35/644A61K2300/00
Inventor 朱志铭赵大鹏张赞李积珍
Owner HEBEI YUZHILIN PHARMA
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