The invention relates to a paper-making white mud based artificial stone preparation method, and belongs to the technical field of waste reuse. Paper-making white mud is used as a base material and milled and mixed with dolomite powder and medical stones to increase activity, citric acid is used for adjusting the alkalinity of mixture and acidizing the mixture, formation of micropores is increased, tetrabutyl titanate and silane coupling agents are added to modify the mixture, compatibility of the mixture and low-density polyethylene is enhanced, the mixture is mixed with the low-density polyethylene, so that the space among the micropores is filled with the low-density polyethylene, strength and water resistance are enhanced, the mixture is finally mixed with cement, bamboo fibers and the like, mixed materials function as micro-crystals, a space mesh structure is filled with the mixed materials, so that solid gel and fiber crystals grow, matrix compaction is increased, and finally, vibration, drying, demolding and maintenance are performed to prepare artificial stones. The paper-making white mud is sufficiently used, resource utilization of waste is realized, and the prepared artificial stones are simple to manufacture and low in cost.