Nano armored protective single-cell product for treating Parkinson's disease through bacteria and preparation method thereof
An armor protection and single-cell technology, which is applied to medical preparations with non-active ingredients, medical preparations containing active ingredients, and pharmaceutical formulas, etc., can solve problems such as probiotic destruction, bacterial death, and limited GABA production capacity, and achieve Reduce inflammatory damage, acceptable effect
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[0033] A nano-armoured protective single-cell product, including liposomes and probiotics encapsulated by liposomes. Liposomes are widely used in drug delivery. The raw materials of liposomes, phospholipids and cholesterol, are stable in the mouth and stomach. After the small intestine, it can only be decomposed under the catalysis of lipase. Liposomes choose soybean lecithin and cholesterol, because they can maintain a stable state in the mouth and stomach, and can be decomposed in the small intestine, exposing the probiotics wrapped in it. It has been verified that liposomes can form a stable lipid film on the surface of BA, which can provide living cells with a strong armor against gastric juice and ensure the activity of cells.
[0034] A method for preparing a nano-armor-protected single-cell product, comprising the following steps:
[0035] S1. Preparation of liposomes: Weigh soybean lecithin, cholesterol and vitamin E in 4:2:1, place in chloroform solvent, stir at room...
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