The invention discloses a nano armored protective single-
cell product, which comprises
liposome and probiotics wrapped by the
liposome, the probiotics are fermented to generate gamma-
aminobutyric acid (GABA), the gamma-
aminobutyric acid (GABA) alleviates the activation of a nigra inflammatory reaction caused by
lipopolysaccharide (LPS) in a PD model, so that the gamma-
aminobutyric acid alleviates the inflammatory damage of nigra
dopaminergic neurons, and plays a role in protecting nerves, and the probiotics are wrapped by the lipidosome, so that the probiotics are protected, and the probiotics are prevented from being damaged by strong acid in
gastric acid and digestive enzymes. According to the nano armored protective single-
cell product for treating Parkinson's
disease through
bacteria and the preparation method thereof, the advantages of nano armored and bacterial treatment are fully utilized, and a single
living cell is decorated by a nano-armored
coating, so that the nano armored protective single-
cell product can not only prevent toxic and side effects caused by overhigh local GABA concentration, but also can maintain the concentration of the GABA in a stable range
in vivo, the half-life period of the GABA is greatly prolonged, and the
neurological rehabilitation effect is greatly improved.