Virtual Reality systems may be used in healthcare and therapy, e.g., focusing on physical and neurorehabilitation. For instance, victims of brain injury may seek treatment to improve, e.g., range of motion, balance, coordination, joint mobility, flexibility, posture, endurance, and strength. VR systems can be used to entertain and instruct patients in their movements while recreating practical exercises to further therapeutic goals. Patient movement data during physical therapy sessions may be valuable to patients and healthcare practitioners. The system may comprise a plurality of body sensors, a VR headset, and a supervisor tablet. The disclosed system may facilitate translation between real world coordinates and virtual world coordinates, assigning sensors to body parts, measuring range of motion of joints and limbs, correcting sensor orientation, recording and presenting therapy data, and generating and animating a 3-D virtual reality avatar in a virtual world to perform activities, among other benefits.