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A kind of medicinal formula and preparation method for treating and preventing arteriovenous fistula dysfunction

A technology of arteriovenous fistula and dysfunction, applied in the field of medical medicine, can solve the problems of inaccurate control of drug dosage and effect, multiple types of components, high cost, and affecting the quality of life of patients, so as to achieve controllable coating amount, Effect of prevention of internal fistula dysfunction and good anti-inflammatory effect

Active Publication Date: 2022-04-12
HANGZHOU RED CROSS HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

When the organization of the hematoma leads to stenosis of the arteriovenous fistula, insufficient blood flow in the fistula and poor function of the internal fistula, it is difficult to achieve sufficient hemodialysis, which will affect the quality of life of the patient
[0003] There are many kinds of existing therapeutic drugs, such as external application of Xiliaotuo, external application of papaya wine, external application of Panax notoginseng, external application of traditional Chinese medicine, etc. However, the traditional Chinese medicines used in the existing external application of traditional Chinese medicine either have simple ingredients and poor effect, or have many types of ingredients. The cost is high, and the existing traditional Chinese medicine is directly applied by adding water to the medicine powder. The residual color of traditional Chinese medicine not only affects the injection of the internal fistula, but also affects the observation of the swelling degree of the internal fistula visually, which will affect the puncture

Method used

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  • A kind of medicinal formula and preparation method for treating and preventing arteriovenous fistula dysfunction
  • A kind of medicinal formula and preparation method for treating and preventing arteriovenous fistula dysfunction
  • A kind of medicinal formula and preparation method for treating and preventing arteriovenous fistula dysfunction

Examples

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Effect test

Embodiment 1

[0035] A medicinal formula and preparation method for treating and preventing arteriovenous fistula dysfunction, which is made of the following raw materials in proportions by weight: 2 parts of safflower, 2 parts of Speranthum folium, 2 parts of Chuanjiao, and 2 parts of Danshen , 2 parts of asarum, 5 parts of chitosan, an appropriate amount of water, an appropriate amount of acetic acid and an appropriate amount of glutaraldehyde aqueous solution.

[0036] Safflower has anti-inflammatory, analgesic, anti-oxidation, anti-coagulant effects, Speranthum has anti-inflammatory, analgesic, anti-bacterial, anti-allergic and in vitro anti-oxidation and antibacterial activities in vitro, Zanthoxylum bungeanum has good in vitro application Anti-inflammatory effect, significant anti-swelling effect and anti-itching effect of the skin. Salvia miltiorrhiza has anti-bacterial and anti-inflammatory effects, scavenging free radicals, anti-oxidation, sedation, and anti-allergic effects. Asarum...

Embodiment 2

[0044] The difference from the above examples is that in the S2 step, 1 part of Safflower, 1 part of Speranthum, 1 part of Chuanjiao, 1 part of Salvia Miltiorrhiza and 1 part of Asarum are taken, and 4 parts of chitosan are taken in the S4 step.

Embodiment 3

[0046] The difference from the above example is that in the S2 step, 3 parts of safflower, 3 parts of Speranthum, 3 parts of Chuanjiao, 3 parts of Salvia miltiorrhiza and 3 parts of Asarum are taken, and 6 parts of chitosan are taken in the described S4 step.

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Abstract

The invention relates to the technical field of medical medicine, and discloses a pharmaceutical formula and preparation method for treating and preventing arteriovenous fistula dysfunction. Polysaccharide, appropriate amount of water, appropriate amount of acetic acid and appropriate amount of glutaraldehyde aqueous solution. The present invention adds safflower, safflower, Sichuan pepper, salvia miltiorrhiza, asarum and chitosan to the medicine, wherein safflower, safflower, Sichuan pepper, salvia and asarum have the effect of promoting blood circulation and removing blood stasis, and shell Glycan is a glucosamine condensation polymer obtained after the deacetylation of the natural product chitin, which has the functions of cell repair, tissue regeneration and gastric mucosal protection, and the degraded product glucosamine has antibacterial and anti-inflammatory effects. Applying to internal fistula blood vessels can effectively prevent internal fistula dysfunction.

Description

technical field [0001] The invention relates to the technical field of medical medicine, in particular to a pharmaceutical formula and preparation method for treating and preventing arteriovenous fistula dysfunction. Background technique [0002] Maintenance hemodialysis (Maintenance hemodialysis, MHD) has become one of the most important methods in the treatment of end-stage renal replacement patients. The establishment of long-term stable and unobstructed vascular access is the guarantee for the smooth progress of MHD treatment. Autologous arteriovenous fistula (AVF) has become the preferred long-term vascular access recognized at home and abroad because of its convenient operation, fewer complications, repeated puncture, stable blood flow, and long service life. It is often called the first choice for MHD patients. lifeline. But another disadvantage is that MHD patients must receive 2-3 dialysis treatments per week, with an average of more than 230-330 punctures per yea...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/722A61K36/758A61K9/06B01D29/01B01D29/96A61J3/00A61K47/36A61P9/14
CPCA61K36/286A61K36/47A61K36/185A61K36/758A61K36/537A61K36/268A61K9/06A61K47/36A61K31/722A61K9/0014A61P9/14A61J3/00B01D29/014B01D29/96A61K2236/331A61K2236/39A61K2236/53A61K2236/51A61K2236/13A61K2300/00
Inventor 卢亚飞石燕许敏霞章莉卜彩芳江卫仙
Owner HANGZHOU RED CROSS HOSPITAL