Preparation method of protein raw material rich in vitamin K2 and functional peptide
A protein raw material and vitamin technology, applied in the field of feed protein, can solve the problems of loss of functional peptides, poor product temperature, fluctuation of enzymatic hydrolysis products, etc., and achieve the effect of reducing loss, reducing emissions and realizing comprehensive utilization.
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Embodiment 1
[0029] a: Preparation of liquid fermentation medium
[0030] 1) Seed medium preparation: 40g / L glucose, 35g / L sucrose, 50g / L peptone, 2.8g / L potassium chloride, 5g / L yeast extract, constant volume with tap water, natural pH, sterilized at 120°C for 15 minutes ;
[0031] 2) Preparation of fermentation medium: 50g / L glucose, 2g / L sucrose, 20g / L glycerin, 30g / L peptone, 10g / L yeast extract, 1g / L dipotassium hydrogen phosphate, constant volume with tap water, natural pH, Sterilize at 118°C for 20 minutes, sterilize the glucose solution separately, and then add it to the fermentation medium according to the above addition ratio;
[0032] b: liquid fermentation
[0033] 1) Bacillus subtilis natto (CICC 10023) was inoculated into a shake flask containing a seed medium, the volume of liquid in the medicine bottle was 10%, the culture temperature was 38°C, the rotation speed of the shake flask was 200r / min, and fermentation was carried out for 18 hours to obtain a seed liquid;
[00...
Embodiment 2
[0041] a: Preparation of liquid fermentation medium
[0042] 1) Preparation of seed medium: 50g / L glucose, 30 g / L sucrose, 30g / L peptone, 2.9g / L potassium chloride, 5g / L yeast extract, constant volume with tap water, natural pH, sterilized at 120°C for 15 minute;
[0043] 2) Preparation of fermentation medium: 45g / L glucose, 10 g / L sucrose, 15 g / L glycerin, 30g / L peptone, 12g / L yeast extract, 0.5g / L dipotassium hydrogen phosphate, constant volume with tap water, pH Naturally, sterilize at 120°C for 15 minutes, and add the glucose solution to the medium according to the proportion after single elimination;
[0044] b: liquid fermentation
[0045] 1) Bacillus subtilis natto (CICC 10023) was inoculated into a shake flask containing a seed medium, the volume of liquid in the medicine bottle was 20%, the culture temperature was 40°C, the rotation speed of the shake flask was 200r / min, and fermentation was carried out for 16 hours to obtain the seed liquid;
[0046] 2) Inoculate ...
Embodiment 3
[0053] a: Preparation of liquid fermentation medium
[0054] 1) Seed medium preparation: 32g / L glucose, 39 g / L sucrose, 30g / L peptone, 3g / L potassium chloride, 4.9g / L yeast extract, constant volume with tap water, natural pH, sterilized at 118°C for 30 minute;
[0055] 2) Preparation of fermentation medium: 60g / L glucose, 0 g / L sucrose, 20g / L glycerin, 40g / L peptone, 8g / L yeast extract, 0.8g / L dipotassium hydrogen phosphate, constant volume with tap water, natural pH , sterilized at 118°C for 30 minutes, and the glucose solution was added to the medium according to the proportion after single elimination;
[0056] b: liquid fermentation
[0057] 1) Bacillus subtilis natto (CICC 10023) was inoculated into a shake flask containing a seed medium, the volume of liquid in the medicine bottle was 15%, the culture temperature was 39°C, the rotation speed of the shake flask was 200r / min, and fermentation was carried out for 12 hours to obtain a seed liquid;
[0058] 2) Inoculate th...
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