Ozone liquid dressing applied to skin diseases and preparation method thereof

A technology for liquid dressings and skin diseases, which is applied to medical preparations with non-active ingredients, medical preparations containing active ingredients, and pharmaceutical formulas. It can solve problems such as uneven quality, unstable ozone, and affecting therapeutic effects. Uniform distribution, good emulsifying effect, simple operation

Pending Publication Date: 2021-12-10
彭彬
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] After ozone dissolves in water, it will become a strong oxidant, which has a strong killing effect on living cells, but ozone is extremely unstable in water. Studies have found that ozone is quite stable in monounsaturated fatty acids, and it can be used to make ozone oil. It has been stored for more than 2 years. Ozonated olive oil is the most used at present, but the price of olive oil on the market is generally expensive, and the quality varies. The duration is short, and a large amount of ozone needs to be added to obtain better results. In addition, the existing ozonated olive oil is difficult to be unacceptable due to its pungent smell, which affects the popularization and application of ozone oil and its related products.
[0004] Camellia oil is rich in unsaturated fatty acids, the content of unsaturated fatty acids exceeds 90%, which is far better than olive oil, and the molecular structure of fatty acids contained in camellia oil is mostly smaller than that of olive oil, without side effects and less greasy feeling. In practice, the ozone in the ozone oil prepared by using camellia oil as the base oil is difficult to mix evenly with the camellia oil, so that the ozone is unevenly dispersed in the camellia oil, and the pure ozone oil is mildly irritating to the intact skin , There is no obvious tingling sensation when ozone oil is applied on non-damaged skin, but there is a tingling sensation when applied to damaged skin; and some people don't like the sticky feeling of ozone oil, so in order to reduce skin irritation and stickiness It is necessary to add skin conditioning active components and water to the ozone oil, but this will cause the prepared ozone liquid to be prone to stratification, which will affect the uniformity of ozone dispersion, and then affect its therapeutic effect

Method used

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  • Ozone liquid dressing applied to skin diseases and preparation method thereof
  • Ozone liquid dressing applied to skin diseases and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Embodiment 1: a kind of preparation method of ozone liquid dressing, it comprises the steps:

[0037] S1: According to the characteristics of different materials, the materials are grouped and mixed according to the amount;

[0038] a. Weigh oat kernel extract, propylene glycol, 1,2-hexanediol, water, and p-hydroxyacetophenone according to the mass ratio of 5%, 55%, 5%, 34%, and 1%, respectively, and mix them into group A share;

[0039] b. According to the mass ratio of 59%, 32%, 1%, and 8%, respectively, water, butanediol, 1,2-hexanediol, and Paeoniae officinalis extract were weighed and mixed into component B;

[0040] S2: Mix the remaining water, glycerin, maltitol, betaine, remaining propylene glycol, trehalose, isopentyl glycol, polyacrylate crosslinked polymer-6, dipotassium glycyrrhizinate, disodium EDTA, and heat To about 85°C, after homogenization, keep warm, and stir to dissolve evenly to obtain component C;

[0041] S3: Mix ozone oil, hydroxyethyl acrylat...

Embodiment 3

[0054] Embodiment 3: application case

[0055] Case 1: Mr. Huang, male, was diagnosed with pustular acne in the Dermatology Department of Chongqing Hospital of Traditional Chinese Medicine. He used the ozone mask prepared in Example 1 and combined it with photodynamic therapy. figure 1 It can be clearly seen that after 20 days of using the ozone mask, the pustules on the affected area did not leak out again, and the swelling of the affected area was obviously reduced. After continuing to use for 40 days, the red and swollen area of ​​the skin was significantly reduced, and some pustules on the skin disappeared completely.

[0056] Case 2: Ms. Li, female, immediately applied the ozone dressing of Example 1 to the surgical site for anti-inflammatory and analgesic effects immediately after chloasma removal.

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Abstract

The invention discloses an ozone liquid dressing applied to skin diseases and a preparation method thereof. The ozone liquid dressing is prepared from ozone oil, water, glycerol, maltitol, betaine, propylene glycol, trehalose, 1, 2-hexanediol, hydroxyethyl acrylate / sodium acryloyldimethyl taurate copolymer, isoprene glycol, ammonium acryloyldimethyl taurate / VP copolymer, methylparaben, dipotassium glycyrrhizinate, polyacrylate cross-linked polymer-6, EDTA (ethylene diamine tetraacetic acid) disodium, an oat kernel extract, p-hydroxyacetophenone, butanediol and a Chinese herbaceous peony root extract. The prepared ozone liquid dressing is good in emulsification effect, uniform in ozone distribution and free of layering phenomenon after being placed for a long time.

Description

technical field [0001] The invention relates to the technical field of medical materials, in particular to an ozone liquid dressing applied to skin diseases and a preparation method thereof. Background technique [0002] Ozone has a strong oxidation effect. Ozone molecules can directly act on the membrane proteins on the surface of bacteria and viruses to denature them, further destroying the DNA and RNA of bacteria and viruses, making them unable to replicate, thereby achieving the effect of sterilization. Because ozone has a killing effect on various bacterial propagules, spores, viruses, herpes, molds and protozoa, the high concentration of oxygen generated during the ozone decomposition process can promote the growth of granulation and the repair of damaged tissues, making it play an important role in the field of medicine. effect. [0003] After ozone dissolves in water, it will become a strong oxidant, which has a strong killing effect on living cells, but ozone is ex...

Claims

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Application Information

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IPC IPC(8): A61L15/18A61L15/24A61L15/40A61L15/44A61L15/46A61K33/00A61K9/70A61K47/46A61P29/00A61P31/02A61P31/04
CPCA61L15/18A61L15/24A61L15/40A61L15/44A61L15/46A61K33/00A61K9/70A61K47/46A61P31/04A61P29/00A61P31/02
Inventor 彭彬
Owner 彭彬
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