Glycyrrhizic anhydride and tremella aurantialba polysaccharide degradation product compound composition and application thereof

A degradation product, glycyrrhizic anhydride technology, which is applied in pharmaceutical formulations, toiletry preparations, medical preparations containing active ingredients, etc., can solve the problem that no one has studied the synergistic effect of glycyrrhizic anhydride and auricium polysaccharide degradation products on moisturizing effect , achieve good moisturizing effect, improve anti-drying ability, and enhance moisturizing effect

Active Publication Date: 2022-01-04
广州萃普生物科技有限公司
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Problems solved by technology

[0006] But the present invention finds that no one has studied the synergistic effect of glycyrrhizic anhydride and auricularia polysaccharide degradation product moisturizing effect in the course of research

Method used

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  • Glycyrrhizic anhydride and tremella aurantialba polysaccharide degradation product compound composition and application thereof
  • Glycyrrhizic anhydride and tremella aurantialba polysaccharide degradation product compound composition and application thereof
  • Glycyrrhizic anhydride and tremella aurantialba polysaccharide degradation product compound composition and application thereof

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Embodiment Construction

[0020] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without creative efforts fall within the protection scope of the present invention.

[0021] Experiment 1: Preparation of golden ear polysaccharide and its degradation products

[0022] Wash and dry the fruiting body of Auricularia aurantium (provided by Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences), grind it with a pulverizer, weigh 30 g of the above dry powder, add 10 times of water, add 3 g of pectinase (purchased from Fluka Company), and enzymatically hydrolyze at 35 ° C for 2 h , then add 20 times of water, soak in boili...

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Abstract

The invention discloses a glycyrrhizic anhydride (GAMS) and tremella aurantialba polysaccharide degradation product (TAP) compound composition. The active ingredients of the compound composition are glycyrrhizic anhydride and tremella aurantialba polysaccharide degradation product. The weight ratio of the glycyrrhizic anhydride to the tremella aurantialba polysaccharide degradation product is (1: 1)-(1: 10). Researches find that the GAMS and the TAP are combined for administration, and especially when the weight ratio is (1: 1)-(1: 10), a very good moisturizing synergistic effect is achieved. According to the glycyrrhizic anhydride (GAMS) and tremella aurantialba polysaccharide degradation product (TAP) compound composition and an application thereof, the protection effect of a sample on dry and damaged HaCaT cells and the influence of the sample on the content of AQP3 in the dry and damaged HaCaT cells are determined according to the determination of in-vitro moisturizing activity, the determination of the transepidermal water loss rates at different times by adding the moisturizing composition into cosmetics, and the results show that the moisturizing composition has the effects of improving the self-drying resistance of the cells at the molecular level. The cosmetic has a strong moisturizing effect.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a compound composition of glycyrrhizic anhydride and auricium polysaccharide degradation product and its application. Background technique [0002] Skin moisturizing is the most basic requirement for skin maintenance. The stratum corneum of human skin is mainly composed of non-nucleated keratinocytes, keratin filaments, amino acid compounds and natural moisturizing factors, which play the functions of maintaining moisture and barrier. The source of water in the stratum corneum of the skin is mainly the sweat secreted by the sweat glands, and 20% of the water is tightly combined with the natural moisturizing factor and skin lipids, thus forming a sebum film emulsified by sweat and water and natural moisturizing Factors become the two most important factors for skin moisturizing. The natural moisturizing factor (NMF), aquaporins (AQPs), tight junction proteins (Claudins), hyalu...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/63A61K8/73A61Q19/00
CPCA61K8/63A61K8/73A61Q19/00A61K2800/592A61K2800/805Y02A50/30
Inventor 涂禄清邓建科
Owner 广州萃普生物科技有限公司
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