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Pharmaceutical composition for treating uremia and preparation method and application thereof

A technology of uremia and composition, which is applied in the field of traditional Chinese medicine composition, can solve the problems of poor therapeutic effect, easy relapse, and poor function of repairing kidney cells, and achieve the effect of convenient administration, good therapeutic effect, and no toxic side effects

Pending Publication Date: 2022-01-14
余焕舟 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Aiming at the deficiencies in the prior art, the present invention provides a pharmaceutical composition for treating uremia and its preparation method and application, which solves the problems in the prior art of repairing kidney cells with poor function, poor therapeutic effect, easy recurrent problem

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0084] The preparation of embodiment 1 pharmaceutical composition

[0085] According to the amount in Table 1, weigh the ingredients of raw materials, Codonopsis pilosula, Schisandra chinensis, Radix Paeoniae Alba, Ligustrum lucidum, Rehmannia glutinosa, Zaopi, Chinese yam, Poria cocos, Cortex paeonol, Eucommia ulmoides, Poguzi, Cyperus cyperi, Wuyao, Gastrodia elata, After the deer horn glue is mixed, add 1500ml of water, soak for 30 minutes, bring to a boil with strong fire, decoct with slow fire for 20 minutes, and filter to obtain the decoction; dry the Cordyceps sinensis in a microwave oven, press into powder, and obtain Cordyceps sinensis powder; Guipi pills can be purchased . The decoction liquid, the powder of Cordyceps sinensis and Guipi Pills form a pharmaceutical composition.

[0086] The proportioning of each raw material in the pharmaceutical composition of table 1

[0087] Ingredients Formula 1 (g) Formula 2 (g) Formula 3 (g) Formula 4 (g) ...

Embodiment 2

[0088] Embodiment 2 pharmaceutical composition is used for the treatment of uremia

[0089] 35 cases of uremia patients were selected, including 20 cases of early stage uremia, 12 cases of middle stage uremia, and 3 cases of late stage uremia; 20 cases were male and 15 cases were female; the oldest was 73 years old and the youngest was 16 years old; the primary diseases included chronic renal failure There were 25 cases of glomerulonephritis, 5 cases of diabetic nephropathy, 2 cases of nephropathy caused by hypertension, 2 cases of tubulointerstitial nephritis, and 1 case of polycystic kidney disease. All cases were consistent with the diagnosis of uremia, Ccr707umol / L.

[0090] Treatment method: use the decoction of Formula 1, 3 times a day, orally in the morning, noon and evening; Cordyceps powder, 2 times a day, in the morning and evening; take the decoction and Cordyceps powder at the same time. Guipi pills are taken 3 times a day, morning, noon and evening.

[0091] Cou...

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PUM

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Abstract

The invention provides a composition for treating uremia and a preparation method and application thereof. The composition comprises the following components in parts by weight: 9-15 parts of codonopsis pilosula, 5-15 parts of schisandra chinensis, 5-7 parts of radix paeoniae alba, 6-15 parts of glossy privet fruit, 6-10 parts of radix rehmanniae preparata, 7-10 parts of fructus corni, 5-15 parts of Chinese yam, 5-15 parts of poria cocos, 5-15 parts of cortex moutan, 5-15 parts of eucommia ulmoides, 7-15 parts of fructus psoraleae, 5-12 parts of cyperus rotundus, 6-15 parts of lindera aggregata, 5-10 parts of gastrodia elata, 5-10 parts of deer-horn glue, 4-6 parts of spleen-invigorating pills and 1-5 parts of cordyceps sinensis. In the formula, through interaction of all the components, the composition has good treatment effects on the early stage, the middle stage and the late stage of uremia, and the total effective rate is 100%.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a pharmaceutical composition for treating uremia, a preparation method and application thereof. Background technique [0002] Uremia is a critical syndrome that occurs due to the retention of nitrogen and other metabolites in the body caused by renal failure, as well as obstacles such as water, electrolyte, and acid-base balance. The prognosis is extremely poor, treatment is difficult, and the mortality rate is high. The main features of uremia are nausea, vomiting, loss of appetite and other gastrointestinal symptoms, accompanied by increased blood urea nitrogen (BUN) and serum creatinine (Scr). At present, the methods for treating uremia mainly contain the following: 1) Hormone drugs: used for the treatment of uremia, but its therapeutic effect is limited, the side effects are very large, and the condition is prone to relapse, treating the symp...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P7/08A61P13/12A61K35/32
CPCA61K36/344A61K36/79A61K36/57A61K36/71A61K36/65A61K36/638A61K36/804A61K36/725A61K36/8945A61K36/076A61K36/46A61K36/487A61K36/8905A61K36/54A61K36/8988A61K35/32A61K36/068A61K36/284A61K36/481A61K36/77A61K36/285A61K36/232A61K36/69A61K36/484A61K36/9068A61K9/0095A61P7/08A61P13/12A61K2236/331A61K2300/00
Inventor 余焕舟张力
Owner 余焕舟
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