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Traditional Chinese medicine cataplasm for treating depression through acupoint application and preparation method of traditional Chinese medicine cataplasm

A technique for acupoint sticking and depression, which is applied in the direction of medical formulas, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc. It can solve the problems of slow disintegration, large doses, improper production operations, etc., and achieve Good adhesion, obvious effect of treating depression

Pending Publication Date: 2022-03-01
JIANGSU 707 NATURAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] As a traditional pill, Yueju pill has a large dose and is inconvenient to take. Improper production and operation can easily cause dissolution, slow disintegration, and slow onset of action.

Method used

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  • Traditional Chinese medicine cataplasm for treating depression through acupoint application and preparation method of traditional Chinese medicine cataplasm

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] A traditional Chinese medicine cataplasm for treating depression by acupoint sticking, which is composed of a backing layer, a medicated plaster layer and a cover lining layer, wherein the medicated plaster layer comprises: 2 parts of medicinal extract, 6 parts of sodium carboxymethyl cellulose, 0.9 parts of hydrogenated rosin methyl ester, 17 parts of glycerin, 2 parts of kaolin, 0.5 parts of aluminum trichloride, and 1 part of azone.

[0035] The medicinal extract is extracted from the following raw materials: 30 parts of Cyperus cyperi, 30 parts of Rhizoma Chuanxiong, 20 parts of fried gardenia, 30 parts of Atractylodes atractylodes, and 50 parts of Liushenqu.

[0036] The backing material used in the backing layer is non-woven fabric, and the cover lining material used in the cover layer is polyethylene film.

[0037] The preparation method of the traditional Chinese medicine cataplasm for treating depression with acupoint application comprises the following steps: ...

Embodiment 2

[0044] A traditional Chinese medicine cataplasm for treating depression by acupoint sticking, which is composed of a backing layer, a medicated plaster layer and a cover lining layer, wherein the medicated plaster layer comprises: 5 parts of medicinal extract, 8 parts of polyacrylic acid, 0.5 part of hydrogenated rosin methyl ester, 16 parts of glycerin, 4 parts of micropowdered silica gel, 0.7 part of aluminum glycylate, and 1 part of borneol.

[0045] The medicinal extract is extracted from the following raw materials: 40 parts of Cyperus cyperi, 35 parts of Rhizoma Chuanxiong, 25 parts of fried gardenia, 40 parts of Atractylodes atractylodes, and 30 parts of Liushenqu.

[0046] The backing material used in the backing layer is non-woven fabric, and the cover lining material used in the cover layer is polyethylene film.

[0047] The preparation method of the traditional Chinese medicine cataplasm for treating depression with acupoint application comprises the following steps...

Embodiment 3

[0054] A traditional Chinese medicine cataplasm for treating depression by acupoint sticking, which is composed of a backing layer, a medicated plaster layer and a cover lining layer, wherein the medicated plaster layer comprises: 6 parts of medicinal extract, 9 parts of carbomer, 1.2 parts of hydrogenated rosin methyl ester, 15 parts of polyethylene glycol, 3 parts of micropowdered silica gel, 0.6 part of aluminum glycylate, and 1.5 parts of polyvinyl pigolidone.

[0055] The medicinal extract is extracted from the following raw materials: 50 parts of Cyperus cyperi, 40 parts of Rhizoma Chuanxiong, 20 parts of fried gardenia, 30 parts of Atractylodes atractylodes, and 35 parts of Liushenqu.

[0056] The backing material used in the backing layer is non-woven fabric, and the cover lining material used in the cover layer is polyethylene film.

[0057] The preparation method of the traditional Chinese medicine cataplasm for treating depression with acupoint application comprises...

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Abstract

The invention provides traditional Chinese medicine cataplasm for treating depression through acupoint application and a preparation method of the traditional Chinese medicine cataplasm. An ointment-containing body layer of the cataplasm comprises the following components in parts by mass: 2-6 parts of a medicine extract, 5-10 parts of a framework material, 0.2-1.3 parts of an adhesive, 12-20 parts of a humectant, 2-6 parts of a filler, 0.5-3 parts of a cross-linking agent and 1-3 parts of a transdermal enhancer, the medicine extract is prepared by extracting the following raw materials: vinegar-processed rhizoma cyperi, ligusticum wallichii, fried fructus gardeniae, rhizoma atractylodis and medicated leaven; the preparation method comprises the following steps: respectively preparing the medicine extract and the blank matrix, adding the transdermal enhancer and the medicine extract into the blank matrix, uniformly stirring, coating on the backing material, and covering with the cover lining layer. The cataplasm disclosed by the invention has good adhesive power, can be adhered to the skin without residues, can be repeatedly uncovered and pasted, and has an obvious depression treatment effect, and in-vitro transdermal drug release can be maintained for 24 hours.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine cataplasm for treating depression by acupoint sticking and a preparation method thereof. Background technique [0002] Yueju Wan is a classic prescription for treating depression in traditional Chinese medicine. The whole prescription is composed of atractylodes rhizome, Cyperus cyperi, Rhizoma Chuanxiong, Divine Comedy and Gardenia. The research team led by Chen Gang, a professor at the Research Center for Translational Systems Biology and Neuroscience, Nanjing University of Traditional Chinese Medicine, discovered that Yueju Pills, a classic traditional Chinese medicine prescription, has a unique rapid and long-lasting antidepressant effect, and revealed its protein kinase B ( Akt) signaling pathway and the mechanism of sustained elevation of brain-derived neurotrophic factor (BDNF). Through a prospective randomiz...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K36/8905A61K47/14A61P25/24
CPCA61K9/7023A61K36/8905A61K36/236A61K36/744A61K36/284A61K36/00A61K47/14A61P25/24A61K2300/00
Inventor 窦宪刘芹
Owner JIANGSU 707 NATURAL PHARMA