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Anti-depression traditional Chinese medicine formula and anti-depression essential oil

An anti-depressant, traditional Chinese medicine technology, applied in pharmaceutical formulations, drug combinations, nervous system diseases, etc., can solve problems such as insignificant improvement effects, and achieve the effects of improving stupor, improving appetite, and wide source of raw materials

Pending Publication Date: 2022-03-18
GUANGDONG UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The Chinese patent with the publication number CN106853172A discloses an antidepressant compound essential oil and its application, but the improvement effect is not obvious

Method used

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  • Anti-depression traditional Chinese medicine formula and anti-depression essential oil
  • Anti-depression traditional Chinese medicine formula and anti-depression essential oil
  • Anti-depression traditional Chinese medicine formula and anti-depression essential oil

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1 antidepressant traditional Chinese medicine prescription and its preparation

[0035] 1. Preparation of various prescriptions of antidepressant traditional Chinese medicine

[0036] Lavender oil, vetiver root oil, jasmine oil, bergamot oil, sandalwood oil, and geranium oil are extracted by steam distillation. The specific extraction steps are as follows:

[0037] (1) Weigh 200 g of pulverized sample powder and place it in a 5000 mL round bottom flask.

[0038] (2) Add 3500mL deionized water and soak for 12 hours respectively.

[0039] (3) Steam distillation for 4 hours to obtain lavender oil, vetiver root oil, jasmine oil, bergamot oil, sandalwood oil, and geranium oil.

[0040] (4) Stir and mix the obtained essential oils evenly in different proportions, the rotating speed of the stirring conditions is 900r / min, and the stirring time is 3min, to obtain final product.

[0041] 2. Prepare antidepressant Chinese medicine prescriptions according to the dosa...

Embodiment 2

[0044] Embodiment 2 antidepressant essential oil and preparation thereof

[0045] 1. Prepare the antidepressant Chinese medicine prescription according to the dosage in Table 2 to prepare the antidepressant essential oil

[0046] Table 2 Antidepressant essential oil ratio

[0047]

[0048] 2. The preparation method of antidepressant essential oil

[0049] (1) Weigh 200 g of pulverized sample powder and place it in a 5000 mL round bottom flask.

[0050] (2) Add 3500mL deionized water and soak for 12 hours respectively.

[0051] (3) Steam distillation for 4 hours to obtain lavender oil, vetiver root oil, jasmine oil, bergamot oil, sandalwood oil, and geranium oil.

[0052](4) will obtain lavender oil, vetiver root oil, jasmine oil, bergamot oil, sandalwood oil, geranium oil and dehydrated alcohol to mix with different proportioning, the rotating speed of stirring condition is 1000r / min, stirring time for 5 minutes, that is.

Embodiment 3

[0053] Efficacy test of embodiment 3 antidepressant essential oil

[0054] The positive effect of the present invention on improving depressive symptoms will be further explained through animal experiment data below.

[0055] The invention adopts the reserpine depression animal model to study the effect of the novel antidepressant compound on the behavior of the depression-like mice through intraperitoneal administration.

[0056] 1. Experimental animals: male BALB / C mice, weighing between 20 and 22 g, provided by the Guangdong Provincial Medical Experimental Animal Center, received 12 hours of light / 12 hours of darkness every day, and the light cycle was 7:00 to 19:00. The room temperature is 25±2°C and the humidity is 60%. The animals can ingest standard feed and clean water by themselves, and the animal experiment operation complies with the international experimental animal ethics requirements. After the mice were adapted to the laboratory for two weeks, the mice were ran...

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Abstract

The anti-depression traditional Chinese medicine formula comprises lavender oil, vetiver root oil, jasmine flower oil, bergamot oil, sandalwood oil and pelargonium graveolens oil, is a composition of essential oil extracted from natural plants, and is wide in raw material source, simple in preparation process, low in cost and suitable for industrial production. The composition has the effects of improving appetite reduction, action reduction and cognitive impairment. The invention further develops the anti-depression essential oil, and the essential oil can relieve depression mood in a targeted manner, and can effectively improve the symptoms of low mood, stiff body, inappetence and slow response.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine compositions, and in particular relates to an antidepressant traditional Chinese medicine prescription and antidepressant essential oil. Background technique [0002] With the development of society and economy, the rhythm is accelerating and the competition is fierce. Under the influence of psychological factors, social factors and human's own bad behavior and lifestyle, the incidence of various psychosomatic diseases in people of different ages is increasing. According to a survey released by the World Health Organization, depression caused by emotional stress affects about 200 to 400 million people in the world every year, and 65% of American professionals have negative emotions prevailing in their hearts. Depression in the present invention refers to major depressive disorder (Majordepressive disorder): with depression, slow thinking and decreased movement as the primary c...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P25/24
CPCA61K36/53A61K36/899A61K36/63A61K36/752A61K36/185A61P25/24A61K2300/00
Inventor 张蓝月石耀辉罗怡杰梁林杰梁晓欣向洪平李春莲
Owner GUANGDONG UNIV OF TECH
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