Method for preparing benzylamine compound through photocatalysis

A compound, benzylamine technology, applied in the field of organic synthesis, can solve problems such as hydrogen instability, dangerous reaction process, and easy explosion, and achieve the effect of universality, high selectivity, and mild conditions

Active Publication Date: 2022-04-29
ZHANGJIAGANG INST OF IND TECH SOOCHOW UNIV +1
View PDF6 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The hydrogen used in the reaction process is very unstable, and the reaction process is very dangerous and prone to explosion

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for preparing benzylamine compound through photocatalysis
  • Method for preparing benzylamine compound through photocatalysis
  • Method for preparing benzylamine compound through photocatalysis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] This embodiment provides a kind of photocatalytic method for preparing benzylamine compound, comprising the following steps:

[0043] (a) the copper / graphene photocatalyst of 50mg 1wt% (the synthesis of copper / graphene photocatalyst is as follows: after 400mg carbon nitride graphene, 53.6mg cupric chloride dihydrate, 2ml ethanol and 50ml water are uniformly mixed, in Under the irradiation of LED lights simulating sunlight and under the protection of nitrogen, stir at room temperature for 2-3 hours, after centrifugation, place in an oven to dry for 24 hours), 80 μmol of benzaldehyde, 200 μmol of absolute ethanol, and 25wt% ammonia water are mixed evenly, and ultrasonic (electric power 80W) dispersed for 10min to obtain a suspension;

[0044] (b) The dispersed suspension is stirred and reacted at room temperature for 6 hours under the irradiation of an LED lamp simulating sunlight and nitrogen protection;

[0045] (c) drying and concentrating the organic phase obtained i...

Embodiment 2

[0048] This embodiment provides a kind of photocatalytic method for preparing benzylamine compounds, which is basically the same as that in Example 1, except that: in step (a), the alcohol used is ethylene glycol; final step (c) As a result, the conversion rate of benzaldehyde is 89% and the selectivity of benzylamine is 82% by gas chromatograph test analysis.

Embodiment 3

[0050] This embodiment provides a kind of photocatalytic method for preparing benzylamines, which is basically the same as that in Example 1, except that: in step (a), the alcohol used is glycerol; the result of final step (c) For testing and analysis by gas chromatography, the conversion rate of benzaldehyde was 79%, and the selectivity of benzylamine was 81%.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention provides a method for preparing a benzylamine compound through photocatalysis. The method comprises the step of enabling an aromatic aldehyde compound to react with ammonia water through a photocatalyst under the conditions of illumination and inert gas to obtain the benzylamine compound. The method for preparing the toluidine compound through photocatalysis can be used for replacing an existing mature organic synthesis process, conditions are mild, selectivity is high, universality is achieved, and the method is suitable for industrial production.

Description

technical field [0001] The invention relates to a method for preparing a compound, in particular to a method for photocatalytically preparing toluidine compounds, and belongs to the technical field of organic synthesis. Background technique [0002] Photocatalytic technology is one of the ideal ways to use solar energy to obtain clean energy. In recent years, photocatalytic organic synthesis technology has provided a green and economical technical route for the synthesis of a variety of high value-added chemicals due to its mild reaction conditions, no need to use additional redox agents, and controllable selectivity. [0003] Benzylamine compounds are important raw materials in industry. As organic synthesis intermediates, they are widely used in fine chemical industry, biomedicine, material synthesis and other industries. The traditional method for synthesizing benzylamine is through the reductive amination of aldehydes and ketones with ammonia and hydrogen. The hydrogen...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): C07C211/27C07C211/29C07C211/53C07C211/49C07C209/24
CPCC07C209/24C07C211/27C07C211/29C07C211/53C07C211/49Y02P20/584
Inventor 张东升苏韧乔玮
Owner ZHANGJIAGANG INST OF IND TECH SOOCHOW UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap