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Preparation method of composite antihypertensive polypeptide edible packaging film

A packaging film and blood pressure-lowering technology, which is applied in the field of preparation of edible packaging film of compound hypotensive polypeptide, can solve the problems of long-term use, easy to produce drug resistance, increase the burden of human liver metabolism, etc., and achieve convenient and low-cost preparation methods , good tensile strength and elongation at break

Pending Publication Date: 2022-05-10
黑龙江省绿色食品科学研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Taking multiple drugs at the same time can easily increase the metabolic burden of the human liver, and long-term use can easily lead to drug resistance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A preparation method of a composite antihypertensive polypeptide edible packaging film, comprising the following steps:

[0025] (1) Grind the soybean grains with a pulverizer, then pass through a 60-mesh sieve, then dissolve the obtained soybean powder into deionized water and adjust the solid-liquid ratio to 6mg / mL, and adjust the temperature to 50°C under the condition of a water bath , adjust the pH value to 8.5, then use Alcalase 2.4L alkaline protease, enzymatically hydrolyze for 3h (enzyme amount 1.85mL / (100g)), then heat at 100°C for 10min to inactivate the enzyme, and put the material at a speed of 8000rmp Centrifuge for 20 minutes, collect the hydrolyzate, and then freeze-dry to obtain the freeze-dried powder of the bioenzyme hydrolyzate;

[0026] (2) Dissolve the freeze-dried hydrolyzate powder obtained in step (1) in deionized water (mass concentration: 40g / L), and heat and stir at 50°C for 20min to reach the optimum temperature of alkaline protease (Alcalas...

Embodiment 2

[0030] The difference between this embodiment and Example 1 is that step (3) is to dissolve 4g soybean polypeptide powder, 4g ovalbumin polypeptide, 1g fructooligosaccharide, 2g chitosan and 0.5g soybean saponin in 110mL of pH5 In deionized water, stir evenly to obtain a mixed solution, and the rest of the operating steps are exactly the same as those in Example 1.

[0031] The content of polypeptide in the packaging film prepared in this embodiment is 40.9%, the content of carbohydrate is 19.8%, the content of soybean saponin is 5.6%, the activity of ACE enzyme is reduced by 70%, and it has better anti-stress effect. Its tensile strength and elongation at break were 40 MPa and 1.6%, respectively.

Embodiment 3

[0033] The difference between this embodiment and Example 1 is that step (3) is to dissolve 4g soybean polypeptide powder, 4g ovalbumin polypeptide, 1g fructooligosaccharide, 2g chitosan and 0.5g soybean saponin in 130mL of 5 pH In deionized water, stir evenly to obtain a mixed solution, and the rest of the operating steps are exactly the same as those in Example 1.

[0034] The content of polypeptide in the packaging film prepared in this embodiment is 32.2%, the content of carbohydrate is 14.2%, the content of soybean saponin is 4.3%, the ACE enzyme activity is reduced by 50%, and it has a certain anti-stress effect. Its tensile strength and elongation at break were 27MPa and 0.6%, respectively.

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Abstract

The invention discloses a preparation method of a composite antihypertensive polypeptide edible packaging film, and belongs to the technical field of food processing. In order to solve the problems that the application range of polypeptide products is not wide enough, side effects exist when various hypertension drugs are taken, and the like, a mixed solution is prepared from soybean protein polypeptide, ovalbumin polypeptide, soyasaponin, chitosan and fructo-oligosaccharide, and then the edible packaging film for assisting in lowering blood pressure is prepared through an electrostatic spinning technology. According to the method, the polypeptide with the antihypertensive effect can be applied to the edible packaging film in an optimal fine distribution mode, so that the edible packaging film has antihypertensive components, a novel eating method of the polypeptide is innovated by an oral fixed dosage form of the edible film, and a new way is opened up for processing and utilizing soybean biological enzymolysis byproducts.

Description

technical field [0001] The invention relates to a preparation method of a composite antihypertensive polypeptide edible packaging film, which belongs to the technical field of food processing. [0002] technical background [0003] Edible packaging film is widely used to package food, such as packaging candy, pastry, medicine, these edible films can be eaten together with food, and its main function is to isolate food, this edible film usually dissolves completely in a short time water. [0004] Soybean protein peptides through biological enzymatic hydrolysis are composed of various amino acids, especially 8 kinds of amino acids necessary for human body. Soybean saponins can promote cholesterol and fat metabolism in the human body, improve myocardial oxygen supply, improve the body's hypoxia resistance function, reduce fat and lose weight, strengthen the activity of central sympathetic nerves, anti-aging, prevent atherosclerosis and other physiological regulation function. ...

Claims

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Application Information

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IPC IPC(8): B65D65/46D01F8/02D01F8/18A23L33/18A23L33/21A23L33/125A23L33/105
CPCB65D65/463D01F8/02D01F8/18A23L33/18A23L33/21A23L33/125A23L33/105A23V2002/00A23V2200/326A23V2250/55A23V2250/284A23V2250/511A23V2250/21
Inventor 孙树坤陈昊李丹许慧郑环宇刘丹怡李杨齐宝坤
Owner 黑龙江省绿色食品科学研究院