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Rapid hemostatic spray and preparation method thereof

A fast, blood-stimulating technology, applied in pharmaceutical formulations, bandages, surgery, etc., can solve the problems of secondary trauma users' skill requirements, slow wound healing of hemostatic materials, etc., to shorten the action time, promote healing, and shorten the reaction route. Effect

Inactive Publication Date: 2022-05-31
SHANGHAI CHANGZHENG HOSPITAL
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] In order to solve the technical problems of slow wound healing of the above-mentioned hemostatic material, easy to cause secondary trauma during the healing process, and high technical requirements for users, the purpose of the present invention is to provide a rapid hemostatic spray and its preparation method

Method used

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  • Rapid hemostatic spray and preparation method thereof

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Embodiment 1

Embodiment 2

[0039] 2 g of chitosan was dissolved in 100 mL of 0.2 M acetic acid, and 100 mL of ethanol was added, heated to 45° C., followed by adding

Embodiment 3

[0044] 2 g of chitosan was dissolved in 100 mL of 0.2 M acetic acid, and 100 mL of ethanol was added, heated to 65° C., followed by adding

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Abstract

The invention discloses a rapid hemostatic spray and a preparation method thereof. The spray comprises hydrophilic and hydrophobic synergistic blood-promoting coagulation gel, a solvent and an auxiliary agent, wherein the hydrophilic and hydrophobic synergistic blood-promoting coagulation gel is formed by physically crosslinking a hydrophobic modified polysaccharide material and a hydrophilic modified polysaccharide material according to a certain proportion. The spray containing the hydrophilic and hydrophobic synergistic blood-promoting coagulation gel prepared by the invention is simple to prepare, has specific synergistic effects between hydrophilic groups and hydrophobic groups and between the groups, and can react with various components in blood at the same time, so that the acting time of a hemostatic material and the blood components is effectively shortened, and the healing of wounds is promoted. Hydrophilic and hydrophobic groups are prepared separately, the reaction route for simultaneously obtaining the hydrophilic and hydrophobic groups is shortened, and the preparation efficiency is improved. The product is in a spray form, can be carried about, can be applied only by pressing a spray head during use, is more convenient to use compared with sponges, dressing patches, hemostatic powder and the like, has low requirements on operating skills of operators, and is more suitable for emergency occasions such as car accidents, war wounds, natural disaster events and the like.

Description

A kind of quick hemostatic spray and preparation method thereof technical field The present invention relates to a kind of medical consumables, relate in particular to a kind of quick hemostatic spray and preparation method thereof. Background technique Bleeding is the main cause of death in trauma patients. In surgical operations, it is often necessary to use bandages. Treat the wound in a way to prevent it from becoming infected. In the process of wound treatment, the most commonly used hemostatic materials are: It is powder, porous sponge, hemostatic gauze and oxidized regenerated cellulose. The technical requirements of the operation are relatively high, and they all have certain defects. It should be attached to gauze for hemostasis; porous sponge and hemostatic gauze have high water absorption, and the surface of the sponge is mainly used in the process of hemostasis. Positive charges adhere and aggregate with platelets, thereby promoting the formation of bl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L24/08A61L24/00A61L26/00
CPCA61L24/08A61L24/0015A61L26/0076A61L26/0023A61L26/0066A61L2400/04A61L2300/216A61L2300/402A61L2300/236A61L2300/412
Inventor 职康康谭梓仪曲乐丰
Owner SHANGHAI CHANGZHENG HOSPITAL
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