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Biological dressing and its preparing method

A biological dressing and biological enzyme technology, applied in the field of scald medicine and wound treatment, can solve the problems of wound adhesion, poor wound ventilation, aggravating the pain of patients, etc., and achieve strong antibacterial effect, suitable softness and good affinity. Effect

Inactive Publication Date: 2004-09-01
徐云龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its shortcoming is: this technology still has not got rid of and uses traditional way, promptly reaches the purpose of antibacterial, sterilizing by means of chemical medicine or antibiotic, thus it is difficult to avoid producing bad stimulation and drug-resistant bacterial strain to human skin, and sticking on the wound especially The compress on the surface of the scalded skin can easily cause poor air permeability of the wound and lead to adhesion with the wound. The new wound surface caused by the removal of wound adhesion will delay the healing of the wound and aggravate the pain of the patient

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～9

[0038] Prepare biological dressings according to the following proportions:

[0039] Example 1 2 3 4 5 6 7 8 9

[0040] Chitosan 1.2 1.3 1.4 1.7 1.8 1.9 2.0 2.1 2.1

[0041] FE complex enzyme 16 16 16 16 16 16 16 16 11

[0042] The inhibition zone data are as follows:

[0043] Example Escherichia coli Pseudomonas aeruginosa Staphylococcus aureus

[0044] 1 18.90 15.84 26.54

[0045] 2 19.62 16.08 26.30

[0046] 3 15.92 12.56 23.40

[0047] 4 15.58 12.42 24.38

[0048] 5 15.60 12.42 24.52

[0049] 6 16.28 11.54 24.52

[0050] 7 16.28 10.70 24.52

[0051] 8 16.94 13.12 24.72

[0052] 9 16.52 11.48 23.22

[0053] The antibacterial data comparison of the sample of Example 3 after 2 weeks of thermal storage at 54°C is as follows:

[0054] Escherichia coli Pseudomonas aeruginosa Staphylococcus aureus

[0055] Before thermal storage After thermal storage Before thermal storage After thermal storage Before thermal storage After thermal storage

[0056] 15.92 19.60 12.56 ...

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PUM

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Abstract

The biological dressing includes chitosan, acetic acid and biological enzyme, preferably FE complex enzyme. It is prepared through dissolving chitosan in distilled water and acetic acid, mixing with biological enzyme via stirring and filtering. It is used in wound treatment, and during treatment, particle dressing is self-degraded into oligosccharide to kill germ fast and to become wound healing agent while the undergraded part forms film natural barrier to inhibit germ's invasion. The present invention has no toxic harm, no allergy and no irritation to body.

Description

technical field [0001] The invention relates to a medicine for treating wounds and scalds, in particular to a natural biomedicine containing chitosan for treating wounds and scalds and a preparation method thereof. Background technique [0002] When the outside of the human body is traumatized, timely treatment must be carried out, such as applying anti-inflammatory and myogenic drugs on the wound, so that the wound can heal as soon as possible. The traditional methods all rely on chemical drugs or antibiotics to achieve antibacterial and bactericidal purposes, so it is difficult to avoid adverse stimulation and drug-resistant strains to human skin. Chinese Patent Application No. 94107473.0 discloses a technology named "Preparation of Chitosan Iodine Wound and Burn Dressing". This patent uses chitosan as a slow-release agent to achieve better antibacterial effect and accelerate wound healing. . Its shortcoming is: this technology still has not got rid of and uses tradition...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F13/02A61L15/38A61L15/44
Inventor 徐云龙刘惠兴
Owner 徐云龙
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