Medication for curing stomach trouble and disease of bills and preparation method

A cholestyramine and cholestyramide drug technology, applied in the preparation of the drug, can solve the problems of poor curative effect of cholestyramine and cholestyramine, side effects of extrapyramidal system syndrome, increased risk of gastric remnant cancer, etc., and achieve good patient compliance , Improve stability and bioavailability, no adverse side effects

Active Publication Date: 2006-06-21
段复华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

(2) Clinical observations also show that after subtotal gastrectomy, the gastric mucosa has serious lesions due to gastroduodenal reflux, and the risk of gastric remnant cancer increases within 15-20 years after operation
However, the former two such as sucralfate, cholestyramine and cholestyramide have poor efficacy; the latter can increase the tension of the lower esophageal sphincter, increase the frequency and intensity of gastric antrum contraction, promote gastric emptying, and reduce bile reflux
However, accelerated gastric emptying only occurs in patients with delayed gastric emptying, and has no effect on patients with normal gastric emptying, and metoclopramide may cause side effects of extrapyramidal syndrome. Pride can cause diarrhea, etc.

Method used

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  • Medication for curing stomach trouble and disease of bills and preparation method
  • Medication for curing stomach trouble and disease of bills and preparation method
  • Medication for curing stomach trouble and disease of bills and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0071] Weigh raw materials (kg) according to the following proportioning ratio:

[0072] Green Leaf Gallbladder 100, Southwest Scutellaria baicalensis 100, Citrus aurantii 100, Bamboo Leaf Bupleurum 100, Paeoniae Alismatis 100, Alisma 50, Poria 50, Yin Chen 40, Bamboo Leaf 25, Rush 25.

[0073] Prepare according to the following steps with the above-mentioned raw materials:

[0074] 1) Pre-treatment of Chinese medicinal materials: sorting, washing, cutting, drying, crushing, sterilizing, drying, crushing, and screening of Chinese medicinal materials into the intermediate warehouse;

[0075] 2) Extraction of traditional Chinese medicine: Grind the clean medicine Gallbladder Folium into fine powder; distill and extract volatile oil from Citrus aurantium and Bupleuri, and collect the distilled aqueous solution in a separate container; soak the dregs and other Qiwei such as Scutellaria baicalensis in water for 12 hours, decoct three times, Each time for 2 hours, filter, combine t...

Embodiment 2

[0078] Weigh raw materials (kg) according to the following proportioning ratio:

[0079] Green Leaf Gallbladder 150, Southwest Scutellaria baicalensis 150, Citrus aurantium 150, Bamboo Leaf Bupleurum 150, Paeoniae Alissa 150, Alisma 100, Poria 100, Capillaris 80, Bamboo Leaf 50, Rush 50.

[0080] Prepare according to the following steps with the above-mentioned raw materials:

[0081] 1) and 2) with embodiment 1.

[0082] 3) Mix the extract and the above-mentioned fine powder, and make tablets according to the method of the prior art.

Embodiment 3

[0084] Weigh raw materials (kg) according to the following proportioning ratio:

[0085] Green Leaf Gallbladder 200, Southwest Scutellaria baicalensis 200, Fructus aurantii 200, Bamboo Leaf Bupleurum 200, Paeoniae Alissa 200, Alisma 150, Poria 150, Capillary 120, Bamboo Leaf 75, Rush 75.

[0086] Prepare according to the following steps with the above-mentioned raw materials:

[0087] 1) and 2) with embodiment 1.

[0088] 3) Mix the extract and the above-mentioned fine powder, and make a powder according to the method of the prior art.

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Abstract

The invention is a medicine for treating biliary-stomach disease and a preparation method thereof. It is a medicine made of the following raw materials in the following weight proportions: 100-200 parts of gallbladder of green leaves, 100-200 parts of southwestern scutellaria baicalensis, 100-200 parts of Citrus aurantium, 100-200 parts of bamboo leaves Bupleurum, 100-200 parts of white peony root, Alisma 50-150, Poria cocos 50-150, capillary 40-120, light bamboo leaves 25-75, rush grass 25-75. The medicine of the present invention has definite curative effect on bile reflux gastritis, bile reflux remnant gastritis and cholecystitis, has no adverse side effects, is cheap, and has good patient compliance. use. This product has a remarkable curative effect on bile reflux gastritis and bile reflux remnant gastritis, the total effective rate of clinical treatment is 90.68%; the total effective rate of the treatment of cholecystitis is 93%. The medicine of the present invention adopts capsules, which changes the inconvenience of taking traditional Chinese medicines, especially for patients who are often on business trips, the capsules overcome these disadvantages and improve the stability and bioavailability of the medicines.

Description

technical field [0001] The invention relates to a medicine for treating gallbladder disease. Specifically, the Chinese patent medicine is prepared from Chinese herbal medicine, and the invention also relates to a preparation method of the medicine. Background technique [0002] Bile reflux is an important reason for the formation of chronic gastritis. In recent years, the role of bile reflux in causing precancerous lesions of gastric mucosa and gastric cancer has been paid attention to. (1)Thomas used BIDA scintillation to measure the amount of duodenal reflux, and found that it had an obvious parallel relationship with the degree of precancerous changes in the gastric mucosa. (2) Clinical observation also shows that after subtotal gastrectomy, the risk of gastric remnant cancer increases within 15-20 years after gastroduodenal reflux causes serious gastric mucosal lesions. [0003] There is currently no effective method for the treatment of bile reflux gastritis. In the...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61K9/14A61K9/20A61K9/48A61P1/04A61P1/16A61K127/00
Inventor 段兴
Owner 段复华
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