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Medicine for treating gout and preparing method

A gout and drug technology, applied in the field of traditional Chinese medicine, can solve the problems of prolonged disease course and painful period of patients, slow effect of controlling symptoms, unacceptable for patients, etc., and achieves the improvement of blood rheology index, suppression of ear swelling, and reduction of UA content. Effect

Inactive Publication Date: 2007-07-18
安徽省药物研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, Western medicine colchicine, allopurinol, probenecid and other drugs are still used in the treatment of gout acute arthritis at home and abroad. Although they can achieve the effect of controlling symptoms, they are unacceptable to patients due to too many toxic and side effects.
Although the existing traditional Chinese medicine has the characteristics of less toxic and side effects, the effect of controlling symptoms is slow, and the patient's course of disease and pain period are prolonged

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Each medicinal ingredient is proportioned according to the following parts by weight: 8 parts of Radix Paeoniae Alba, 7 parts of Paeoniae officinalis, 7 parts of Mori twigs, 4 parts of Wexensis, 7 parts of Coix Seed, 8 parts of Smilax, 4 parts of Achyranthes Radix, Lingxian 4 parts, Astragalus 8 parts. The formula with this ratio is suitable for early stage patients with mild disease.

[0019] Concrete preparation process is as follows:

[0020] According to the above proportions, weigh white peony root, fennel, mulberry twig, sage, coix seed, smilax, achyranthes bidentata, clematis, and astragalus, add 8 times the amount of water to decoct three times, each time for 1 hour, and combine Decoction three times, filter, concentrate the filtrate to a clear paste with a relative density of 1.10 (60°C thermal measurement), let it cool, add ethanol to the clear paste to make the alcohol content reach 60%, stir well, let stand for 24 hours, pour Take the supernatant, filter, ...

Embodiment 2

[0022] Each medicinal ingredient is proportioned according to the following parts by weight: 15 parts of Radix Paeoniae Alba, 12 parts of Moss officinalis, 12 parts of Mori twig, 10 parts of Wexenia chinensis, 12 parts of coix seed, 15 parts of Smilax cocos, 10 parts of Sichuan Achyranthes bidentata, Lingxian 10 parts, Astragalus 15 parts.

[0023] The formula with this ratio is suitable for patients with severe symptoms of gout who have been in the condition for more than 3 years.

[0024] Concrete preparation method is with embodiment 1.

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Abstract

The invention is a medicine for curing arthrolithiasis and the preparing method thereof, characterized by that it is prepared of White Paeony Root, Fenbixian, Mulberry Twig, Herba Siegesbeckiae, Coix Seed, Glabrous Greenbrier Rhizome, Medicinal Cyathula Root, Clematis Root, and Membranous Milkvetch Root in certain proportion and able to be made into any oral form. It has functions of clearing heat and discharging corruption, tonifying spleen and promoting diuresis, and dispelling the wind and removing rheumatism and is used for curing diseases caused by damp, heat, accumulation and mass, especially pains in limbs, muscles and veins, red and swelling, fever and pains of joint, and inconvenient bending and extending. The curative effect study verifies that it can reduce the uric acid content of the blood serum of an animal with high- uric acid content blood disease, improve rheological indexes of the blood, and treat gouty arthritis and common inflammation and has good pain-stopping function and very curative effect on acute and chronic grouts, where the clinical effective rate is up to 91.36%.

Description

Technical field: [0001] The invention relates to a medicine for treating gout and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique: [0002] Gout is a rheumatic disease caused by a disorder of purine metabolism. Clinically, it is characterized by hyperuricemia with recurrent attacks of gouty acute arthritis, tophi deposition, gouty chronic arthritis and joint deformities, substantive lesions such as glomeruli and renal tubules, and uric acid stone formation. The course of the disease is long, and in the later stage, renal failure, arteriosclerosis, coronary heart disease, and cerebrovascular accident are often complicated. Gout is a common disease, and the acute arthritis phase of gout has caused unbearable pain to the patient. So far, Western medicine colchicine, allopurinol, probenecid and other drugs are still used in the treatment of gout acute arthritis both at home and abroad. Although they can achieve the ef...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61K36/896A61K36/8945A61K36/716A61K36/71A61K36/605A61K36/481A61K36/28A61K36/21A61K9/16A61P19/06
Inventor 方朝晖
Owner 安徽省药物研究所
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