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Fast diagnosis reagent for genital tract chlamydia trachomatis

A technology for rapid diagnosis of Chlamydia trachomatis, applied in biochemical equipment and methods, and microbial measurement/inspection, etc., can solve the problems of many interfering microorganisms, low coincidence rate, large urine interference, etc., and achieve simple operation and high coincidence rate , the effect that is easy to judge

Inactive Publication Date: 2003-05-14
AUTOBIO DIAGNOSTICS CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantage is that the urine interference is relatively large, there are many interfering microorganisms in clinical practice, and the coincidence rate is low

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Embodiment 1, genital tract chlamydia trachomatis rapid diagnostic reagent, is made up of separate base liquid and chromogenic agent, and base liquid is the sodium chloride aqueous solution of concentration 0.8g / 100ml, is contained in the reaction tube; chromogenic agent is anthrone And the aqueous solution of sulfuric acid, the concentration of anthrone is 0.2g / 100ml, the concentration of sulfuric acid is 100ml 98% sulfuric acid / 100ml, dress in the developer bottle. The preparation method is as above.

Embodiment 2

[0013] Embodiment 2. In this embodiment, the base liquid is an aqueous sodium chloride solution with a concentration of 0.9g / 100ml, the concentration of anthrone in the developer is 0.1g / 100ml, and the concentration of sulfuric acid is 70ml 98% sulfuric acid / 100ml. Others are the same as embodiment 1.

Embodiment 3

[0014] Embodiment 3. In this embodiment, the base liquid is an aqueous solution of sodium chloride with a concentration of 1.2g / 100ml, the concentration of anthrone in the developer is 0.15g / 100ml, and the concentration of sulfuric acid is 75ml 98% sulfuric acid / 100ml. Others are the same as embodiment 1.

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PUM

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Abstract

The present invention relates to diagnosis reagent technology. The fast diagnosis reagent for genital tract Chlamydia trachomatic consists of separate base liquid and color developing agent. The baseliquid is water solution of sodium chloride in the concentration of 0.5-10 g / 100ml. The color developing agent is the water solution of anthrone and sulfuric acid and concentration of anthrone is 0.5-10 g / 100ml, concentration of sulfuric acid is 10-100 ml 98% sulfuric acid / 100 ml. The color developing agent contains also antioxidant comprising sulfourea and cysteine. The reagent has sensitivity of 84.8-87.5%, specificity of 96.5-98.6% and thus high clinical use value.

Description

technical field [0001] The invention belongs to the technical field of diagnostic reagents, in particular to a rapid diagnostic reagent for Chlamydia trachomatis in the reproductive tract. Background technique [0002] Chlamydia trachomatis is a pathogen that can be widely disseminated in the population, and its influence in sexually transmitted diseases (STDs) is becoming more and more significant. It has surpassed gonorrhea and has become the STD with the highest incidence rate, accounting for about 40-60%. Chlamydia trachomatis infection can cause urethritis, orchitis and epididymitis in men, urethritis, cervicitis and salpingitis in women, neonatal inclusion body conjunctivitis and pneumonia in infants and young children, as well as infertility and miscarriage symptoms. The detection of chlamydia infection has been taken as a mandatory item for genitourinary system symptoms (including infertility, infertility, pre-pregnancy, pre-natal, pre-abortion, etc.) in foreign cou...

Claims

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Application Information

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IPC IPC(8): C12Q1/04C12Q1/25
Inventor 王则宇付光宇陈睿锋秦耘杨增利彭志刚苗兰芳朱新朋
Owner AUTOBIO DIAGNOSTICS CO LTD
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