Resorbable micro-membrane for attenuation of scar tissue

A tissue and scar technology, which is applied in the field of medicines and tools formed by postoperative adhesions

Inactive Publication Date: 2003-12-31
MAST BIOSURGERY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Various forms of barrier materials, such as membranes and viscous intraperitoneal solutions, have been designed to limit tissue apposition with limited success

Method used

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  • Resorbable micro-membrane for attenuation of scar tissue
  • Resorbable micro-membrane for attenuation of scar tissue
  • Resorbable micro-membrane for attenuation of scar tissue

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Embodiment Construction

[0040] The present invention provides absorbable implants in the form of films that can be used in various surgical settings to hinder or prevent tissue adhesions and reduce scarring. The polylactide polymers and copolymers of the present invention require relatively simple chemical reactions and formulations. The scar-reducing absorbable barrier films of the polylactide polymers and copolymers of the present invention are believed to be capable of inducing relatively little localized tissue inflammation, but this inflammation is believed to be minimized due to the currently designed composition as described herein , structure and application, thereby reducing scar tissue very effectively.

[0041] The scar reducing absorbable barrier film of the present invention can be more effective than other films because it is very smooth and non-porous. Furthermore, the barrier membrane is preferably bioabsorbable in vivo. The lack of porosity acts as a barrier that does not allow tis...

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Abstract

Resorbable polylactide polymer scar tissue reduction barrier membranes and methods of their application are disclosed. The scar-tissue reduction barrier membranes are constructed entirely ofpolylactide resorbable polymers, which are engineered to be absorbed into the body relatively slowly over time in order to reduce potential negative side effects. The scar tissue reduction barrier membranes are formed to have thicknesses on the order of microns, such as, for example, thicknesses between 10 and 300 microns. The membranes are preshaped with welding flanges and stored in sterile packaging.

Description

[0001] related application [0002] This application claims priority under 35 U.S.C. 119(e) to Provisional Application Nos. 60 / 231,800, filed September 11, 2000, and 60 / 196,869, filed March 10, 2000. field of invention [0003] The present invention relates generally to devices, and more particularly to devices and methods for attenuating post-operative adhesion formation between a post-surgical site and adjacent surrounding tissue. Background of the invention [0004] A major clinical problem associated with surgical recovery or inflammatory disease is adhesions, which occur during the initial stages of the healing process after surgery or disease. Adhesions are conditions that involve the formation of abnormal tissue connections. These connections that form can impair body function, produce infertility, block the bowel from the rest of the gastrointestinal tract (ileus) and produce widespread discomfort, such as pelvic pain. The condition can be life-threatening. The mo...

Claims

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Application Information

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IPC IPC(8): A61L27/00A61F2/00A61F2/02A61F2/10A61F13/00A61L15/16A61L17/12A61L31/06
CPCA61F2/0059A61B17/70A61F2210/0004A61F2002/30062A61L31/06C08L67/04A61F2/00
Inventor C·J·卡尔霍恩R·E·霍尔梅斯
Owner MAST BIOSURGERY
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