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Chinese medicine for treating osteoporosis and its preparation method

A technology for osteoporosis, liver and kidney deficiency, applied in pharmaceutical formulas, unknown raw materials, medical preparations containing active ingredients, etc., can solve problems such as major side effects, easy rebound after drug withdrawal, and achieve drug safety and no toxic side effects. Effect

Active Publication Date: 2004-05-05
JIANMIN PHARMA GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the commonly used western medicines are mainly calcium, estrogen, calcitonin and other drugs that are beneficial to calcium absorption and inhibition of osteolysis. In the treatment of osteoporosis, it mainly focuses on overall regulation and has obvious advantages

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Take 10Kg of Moutan Cortex and add water to distill for 4 hours to extract paeonol, separate paeonol and dry at low temperature, grind it into fine powder for later use; mix distilled Moutan Cortex dregs with Rehmannia glutinosa 30Kg, dog ridge 10Kg, dogwood 10Kg, yam 10Kg , Angelica 10Kg, and Epimedium 10Kg are decocted twice with water, combined and concentrated into an extract with a relative density of 1.30, mixed with an appropriate amount of starch and granulated, and added an appropriate amount of magnesium stearate to the prepared granules As a lubricant, tableting promptly obtains the tablet of the present invention.

[0036]The traditional Chinese medicine tablet of the present invention has the functions of nourishing the liver and kidney, strengthening tendons and bones, and is mainly used for primary osteoporosis caused by deficiency of liver and kidney. doctor's order.

Embodiment 2

[0038] Take 30Kg of Moutan cortex and add water to distill for 4 hours to extract paeonol, separate paeonol and dry at low temperature, stir paeonol and 4 times the amount of β-cyclodextrin in water for 1 and a half hours, the temperature is controlled at 40 ° C, and then Cool to precipitate crystals, filter, dry, and crush the crystals to obtain the clathrate of paeonol for later use; take 20Kg of Cornus officinalis, 30Kg of Angelica sinensis, and 10Kg of Epimedium and extract them with ethanol. The specific method is: the above three medicinal materials are placed in a heat reflux device Add 50% ethanol to reflux twice, combine the medicinal liquid to recover ethanol and concentrate it under reduced pressure to a certain density of extract; weigh 70Kg rehmannia glutinosa, 15Kg yam, 20Kg dog ridge and 40Kg oyster (calcined), and return part of the medicinal residue with ethanol Merge, decoct twice with water, combine the medicinal liquid and concentrate under reduced pressure ...

Embodiment 3

[0040] In this embodiment, the preparation method, functions and indications, usage and dosage of the medicine are the same as in Example 2, except that the dosage of the medicinal materials in the prescription is different. The dosage of the medicinal materials is: Moutan bark 20Kg, dogwood 25Kg, angelica 25Kg, epimedium 25Kg, rehmannia glutinosa 50Kg, yam 15Kg, dog ridge 25Kg and oyster (calcined) 38Kg.

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PUM

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Abstract

A Chinese medicine for treating the primary osteoporosis is prepared from 8 Chinese-medicinal materials including rehmannia root, yam, Chinese angelica root, tree peony bark, etc through extracting in alcohol or water, peonol extracting, concentrating and shaping.

Description

technical field [0001] The invention belongs to a kind of traditional Chinese medicine, in particular, it is a kind of traditional Chinese medicine mainly used for treating primary osteoporosis with liver and kidney deficiency syndrome, and the invention further provides a preparation method thereof. Background technique [0002] Osteoporosis is a disease of abnormal bone metabolism. Its pathogenesis is not yet clear. It is generally believed to be related to human aging and endocrine disorders. It has a high incidence rate and great harm, and is currently listed as a common disease of the elderly alongside arteriosclerosis and tumors. At present, the commonly used western medicines are mainly calcium, estrogen, calcitonin and other drugs that are beneficial to calcium absorption and inhibition of osteolysis. In the treatment of osteoporosis, it mainly focuses on overall regulation and has obvious advantages. The effect of traditional Chinese medi...

Claims

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Application Information

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IPC IPC(8): A61P19/10
Inventor 熊富良张惠明黄志军曹智华徐绍新许沛虎梁前荣鞠瑞芬
Owner JIANMIN PHARMA GRP CO LTD
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