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Compound ginkgo leaf reparation and its making method

A technology of ginkgo biloba leaves and preparations, applied in the field of compound ginkgo biloba preparations and their preparation, can solve problems such as limited cerebrovascular diseases, and achieve the effects of advanced quality control means, improved content and quality control standards, and large specific surface area.

Active Publication Date: 2004-07-21
天津金士力健康用品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] From the above introduction, we can see that Ginkgo biloba is an excellent drug for treating cardiovascular and cerebrovascular diseases. There are very few reports on the current compound ginkgo preparations, and the application to cerebrovascular diseases is even more limited.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0136] (1) Preparation of Ginkgo biloba extract: Take 1000g Ginkgo biloba and grind it, use 5 times the amount of acetone:water (70:30) mixture to heat and extract twice, each time for 2 hours, the temperature is 50-60°C, and combine the extracts , filtered, concentrated under reduced pressure into 280g of Ginkgo biloba extract;

[0137] (2) Preparation of ginseng extract: Take 100 g of ginseng slices, add 8 times the amount of water, extract 2 times, each time for 3 hours, combine the extracts, concentrate, and concentrate until each 5 ml contains 1 g of ginseng medicinal materials to obtain 40 g of ginseng extract;

[0138] (3) get Rhizoma Chuanxiong, pulverize, adopt water distillation method, obtain the volatile oil of Rhizoma Chuanxiong 80g;

[0139] (4) Take the above-mentioned ginkgo extract and ginseng extract, add absolute ethanol to make them fully dispersed, mix evenly, control the temperature at 60°C, and control the alcohol content at 4% of the total dose;

[014...

Embodiment 2

[0142] (1) Preparation of Ginkgo biloba extract: Ginkgo biloba is crushed, added 5 times the amount of 65% ethanol to reflux extraction twice, each time for 2 hours, the temperature is 60 ° C, combined extracts, filtered, concentrated under reduced pressure and recovered ethanol to obtain Ginkgo biloba extract 280g;

[0143] (2) Preparation of ginseng extract: Take ginseng slices, add 8 times the amount of 70% ethanol, extract twice, each time for 3 hours, combine the extracts, recover ethanol, concentrate until each 5ml contains 1g ginseng medicinal materials, and obtain ginseng extract 40g;

[0144] (4) get Rhizoma Chuanxiong, pulverize, adopt hydrodistillation method, obtain the volatile oil of Rhizoma Chuanxiong 80g;

[0145] (5) Take the above-mentioned ginkgo extract and ginseng extract, add absolute ethanol to make them fully dispersed, mix evenly, control the temperature at 60°C, and control the alcohol content at 4% of the total dose;

[0146] (6) Mix ginkgo biloba,...

Embodiment 3

[0148] (1) Mix 340g of Ginkgo biloba extract, 20g of ginseng extract and 40g of Chuanxiong volatile oil to make drop pills.

[0149] (2) get Rhizoma Chuanxiong, pulverize, adopt supercritical extraction method, obtain the volatile oil of Rhizoma Chuanxiong 40g;

[0150] (3) The preparation method of Ginkgo biloba extract and Ginseng extract is the same as in Example 2.

[0151] Among them, the ginkgo extract and ginseng extract in step 1 are added with absolute ethanol to make them fully dispersed, mixed uniformly, the temperature is controlled at 60 ° C, and the alcohol content is controlled at 4% of the total dose; the ginkgo leaves and ginseng extracts Mix well with the Rhizoma Chuanxiong volatile oil, add polyethylene glycol 6000, dissolve the material at 60°C, and drop it into drop pills.

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PUM

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Abstract

A Chinese medicine for preventing and treating coronary heart disease and angina pectoris, and protecitng the cerebral ischemic injury is prepared from ginkgo leaf extract, ginseng extract, and the volatile oil of chuan-xiong or borneol.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation and a preparation method thereof, in particular to a compound ginkgo leaf preparation and a preparation method thereof. Background technique [0002] Ginkgo biloba is the leaf of Ginkgo biloba L. Contains flavonoids (more than 20 kinds), terpenoids, phenols, beneficial trace elements and 17 kinds of amino acids and other active ingredients, which can reduce serum cholesterol, increase coronary blood flow, improve cerebral blood circulation, relieve smooth muscle spasm, relax bronchi and Antibacterial and other pharmacological effects. Clinically, it is not only used in the treatment of cardiovascular and cerebrovascular diseases, but also has good effects on the nervous system and respiratory system. Scientists such as France and Germany have confirmed that Ginkgo biloba extract has significant curative effects in the treatment of cerebral ischemia, ...

Claims

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Application Information

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IPC IPC(8): A61K31/704A61P9/00
Inventor 叶正良章顺楠孙鑫
Owner 天津金士力健康用品有限公司
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