Use of lactalapoprotein in prevention and treatment of microbial or virus infection

Abstract

The present invention relates to use of a milk apoprotein or a mixture thereof to prevent or treat microbial or viral infection of the human or animal body. It is believed that this is achieved by inhibiting adhesion of potential pathogens. More preferably, at least one milk apoprotein or a mixture thereof is administered, simultaneously or sequentially, with either or both of at least one free fatty acid or a mixture thereof or a monoglyceride thereof; and / or at least one organic acid or a salt or ester thereof or a mixture thereof. The active agent(s) may be delivered by means of a pharmaceutically acceptable delivery system which includes parenteral solutions, ointments, eye drops, nasal sprays, intravaginal devices, surgical dressings, medical foods or drinks, oral healthcare formulations and medicaments for mucosal applications.

Description

[0001] The present invention relates to the use of milk apoprotein in preventing or treating the infection of human body or animal body by microorganism or virus. More specifically, these milk apoproteins can be used alone or in combination with one or more short-chain organic acids (such as citric acid) and their salts or esters, and / or one or more free fatty acids and their used in combination with monoesters to inhibit the adhesion and / or growth of potential pathogens. Background of the invention

[0002] Milk is a whitish fluid produced by the mammary glands of mature female mammals after giving birth. Mammals are warm-blooded vertebrates belonging to the class Mammalia, including humans. More preferred mammals for the purposes of the present invention are ungulate artiodactyls belonging to the suborder Ruminants, such as cattle, sheep, goats, deer and giraffes. In the present invention, milk from cows and goats is the preferred source of milk apoprotein simply because m...

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