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Dripping pill made from haw, chrysanthemum and Chinese wolfberry fruit and its preparing method

A technology of medlar and mountain flower, which is applied in the directions of pill delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of unfavorable overall health level, low dissolution rate, unfavorable to improve the ability of patients to seek medical treatment, etc. Labor protection and environmental protection, the effect of accelerating dissolution and absorption, and improving bioavailability

Inactive Publication Date: 2005-10-19
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
Granules also have relatively low drug content, which is inconvenient to take and other deficiencies
[0008] In addition, conventional oral dosage forms, such as tablets, capsules, granules (infusions), etc., due to the granulation process in the preparation process, will generate relatively large dust pollution, which will cause health problems to the staff to a certain extent. harm, and also cause some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0028] Now with several groups of specific examples, the preparation method of Shanhuajing dripping pills of the present invention is further described:

[0029] Group 1: Tests with a single matrix

[0030] 1. Preparation of the drug extract: according to the preparation method 1, first prepare the dry powder of the drug extract for later use;

[0031] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc.;

[0032] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0033] 4. Prepare according to the process given in [Preparation Method] 4-7 ​​to obtain Shanhuajing dripping pills of different specifications.

[0034] [test results]

[0035] Experiment 1: In order to observe the difference in quality of the Shanhuajing dripping pills prepared when the ratio of ...

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PUM

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Abstract

The haw-chrysanthemum-wolfberry fruit dripping pill has the functions of nourishing liver and kidney, eliminating liver heat and strengthening eyesight, and is used in treating Yin deficiency and Yang hyperactivity, headache and dizziness, hypertension, hyperlipemia, etc. The haw-chrysanthemum-wolfberry fruit dripping pill is prepared with haw, chrysanthemum and wolfberry fruit as main material as well as matrix carrier, and has high bioavailability, fast acting, high effective content, taking convenience and low cost.

Description

technical field [0001] The invention relates to a pharmaceutical composition which has the functions of nourishing the liver and kidney, clearing the liver and improving eyesight, and is used for the treatment of diseases such as yin deficiency and yang hyperactivity, headache, dizziness, hypertension and hyperlipidemia, especially hawthorn (stir-fried), chrysanthemum A kind of pharmaceutical composition oral drop pill preparation prepared from 3 flavors of traditional Chinese medicines such as Fructus Lycii and Wolfberry as raw materials. Background technique [0002] According to the ministerial drug standard WS 3 -Shanhua Jing Granule prepared by the preparation method given in B-0679-91 is a kind of nourishing liver and kidney, clearing liver and improving eyesight, and it is used for deficiency of yin and hyperactivity of yang, headache and dizziness, as well as hypertension and hyperlipidemia Oral granules for the treatment of diseases such as inflammatory bowel disea...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61P1/14A61P3/06A61P9/12
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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