Xinnaoshu dripping pill for invigorating qi and nourishing yin and its preparing method

A technique for both qi and yin deficiency and dizziness. It is applied to medical preparations containing active ingredients, pill delivery, and pharmaceutical formulas. It can solve problems such as low dissolution rate, inconvenient taking or carrying, and low drug content, and achieve dissolution and accelerated absorption, improved bioavailability, and high degree of automation

Inactive Publication Date: 2005-10-19
北京博智绿洲医药科技有限公司
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AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
However, syrup oral preparations also have disadvantages such as low drug content, difficulty in taking and measuring accurately, inconvenient taking or carrying, etc.
[0008] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0035] The preparation method of Xinnaoshu dripping pills of the present invention will be further described with several groups of specific examples.

[0036] Group 1: Tests with a single matrix

[0037] 1. Preparation of drug extracts: According to [Appendix], firstly prepare the dry powder of extracts containing active pharmaceutical ingredients of 5 traditional Chinese medicines, including ginseng, Ophiopogon japonicus, Schisandra chinensis, Codonopsis pilosula, and Astragalus membranaceus;

[0038] 2. Substrate: polyethylene glycol (1000、2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0039] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0040] 4. Prepare according to the process given in [Preparation Method] 4-7 ​​to obtain Xinnaoshu Dropping Pills of different specifications.

[0...

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PUM

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Abstract

The present invention relates to a kind of medicine composition, Xinnaoshu dripping pill, for treating insomnia, amnesia, heart palpitation, night sweat, irritabiity, etc. caused by vital energy and yin deficiency. The present invention has high bioavailability, fast medicine release, fast acting, high effective content, taking convenience and low cost. The Xinnaoshu dripping pill is prepared with five kinds of Chinese medicinal materials of ginseng, ophiopogon root, schisandra, Dangshen and astragalus root and medicine carrier as matrix.

Description

technical field [0001] The present invention relates to a pharmaceutical composition which has the function of invigorating qi and nourishing yin, and is used for the treatment of dizziness, insomnia, forgetfulness, palpitation, shortness of breath, fatigue, spontaneous sweating, and impatience caused by deficiency of both qi and yin. In particular, it relates to an oral preparation of a pharmaceutical composition prepared from extracts of active pharmaceutical components of five traditional Chinese medicines, such as ginseng, Ophiopogon japonicus, Schisandra chinensis, Codonopsis pilosula, and Astragalus membranaceus. Background technique [0002] Guiqishen Oral Liquid, which is prepared according to the preparation method given in the ministerial drug standard WS3-B-3152-98, has the effect of nourishing qi and nourishing yin, and is used for dizziness caused by deficiency of both qi and yin. Insomnia, forgetfulness, palpitations, shortness of breath, fatigue, spontaneous s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61P1/14A61P25/20
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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