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Orally administered dripping pills with diuresis inducing function and preparation process thereof

A diuretic tonic and dripping pill technology, which is applied to medical preparations containing active ingredients, pill delivery, pharmaceutical formulas, etc., can solve the problems that are not conducive to improving the patient's ability to seek medical treatment, the bioavailability of the first-pass effect of the liver and intestines, and the overall health level and other issues, to achieve the effects that are conducive to labor protection and environmental protection, improve bioavailability, and drug safety

Inactive Publication Date: 2006-02-08
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
In addition, conventional oral dosage forms, such as tablets, capsules, granules (infusions), etc., due to the granulation process in the preparation process, will generate relatively large dust pollution, which will cause health problems to the staff to a certain extent. harm, and also cause some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0031] Now with several groups of specific examples, the preparation method of Bining dropping pills of the present invention will be further described.

[0032] [recipe selection]

[0033] 1. Raw materials: Pre-prepared dry powder of medicinal extracts with high purity according to Appendix 2 for future use;

[0034] 2. Single matrix: polyethylene glycol 1000 , polyethylene glycol 4000 , polyethylene glycol 6000 , polyethylene glycol 10000 , polyethylene glycol 20000 , Span 40, polyoxyl 40 stearate, poloxamer, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc.;

[0035] 3. Combination matrix: take g or kg as the unit, by weight, choose polyethylene glycol, polyoxyl 40 stearate, sodium carboxymethyl starch, beta cyclodextrin, Tween and other carriers for combination test;

[0036] 3.1 The combination of two different substrates: take g or kg as the unit, by weight, take 1 part of polyoxyl 40 stearate or beta cyclodextrin or sodium carb...

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PUM

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Abstract

The invention relates to orally administered dripping pills with diuresis-inducing function and preparation process, which is prepared from Chinese medicinal herbs including chinaure, plantain herb, creeping oxalis, and medicinal carrying agent as the base material. The dripping pills have the advantages of high biological availability, quick-speed medicine release, quick-speed effect, higher medicinal content, easy administering, low price, and no contamination in production.

Description

technical field [0001] The present invention relates to a kind of medicine composition that has clearing away heat and detoxifying, diuresis and treating stranguria, and is used for the treatment of yellow-red urine, scorching heat and stinging pain, abdominal cramps and other diseases caused by accumulation of moist heat. An oral preparation of a pharmaceutical composition prepared from extracts of active ingredients of three traditional Chinese medicines such as plantain and wood sorrel as raw materials. Background technique [0002] Bining Capsules, prepared according to the preparation method given in the national drug standard WS-11200 (ZD-1200)-2002, is a kind of capsule that has the functions of clearing away heat and detoxification, diuresis and treating stranguria, and is used for urination caused by accumulation of damp heat. Oral tablets for the treatment of yellow red, burning and tingling pain, lower abdomen urgency, etc., have been clinically verified for many ...

Claims

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Application Information

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IPC IPC(8): A61K36/75A61K9/20A61P13/02A61P13/00
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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