Compound yew drop pills and its preparation method

A technology of compound red bean and Shanshan dripping pills, which is applied in the fields of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc. It can solve the problems of immature preparation of dripping pills, increase of drug costs for patients, and affect the accuracy of dosage, etc. problem, to achieve the effect of improving bioavailability, low production cost and high yield

Inactive Publication Date: 2006-02-15
北京博智绿洲医药科技有限公司
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Problems solved by technology

[0011] Yet, because the preparation technology of drop pill is not yet very mature, and its related equipment has not yet reached the degree of standardization, when utilizing existing technology to prepare drop pill, product quality is affected by the physicochemical property of medicine, the kind of matrix and its mixing with medicine. Influenced by factors such as ratio, condensing agent and its temperature, indicators such as rounding rate and difference in pill weight are quite different from the quality indicators of dripping pill preparations stipulated in the national drug standards. Such products seriously affect the dosage in use. The accuracy of the product also reduces the qualified rate of the product in production, increases the production cost, and indirectly increases the drug cost of the patient, thus reducing its practicability

Method used

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Examples

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Embodiment Construction

[0034] Now with several groups of specific examples, the preparation method of compound yew dripping pills of the present invention will be further described.

[0035] [recipe selection]

[0036] 1. Raw materials: according to the [Appendix], pre-prepared dry powder extracts containing the active ingredients of 3 traditional Chinese medicines such as yew, red ginseng, and licorice, and set aside;

[0037] 2. Single matrix: selected from polyethylene glycol 1000 , polyethylene glycol 4000 , polyethylene glycol 6000 , polyethylene glycol 10000 , polyethylene glycol 20000 , Span 40, polyoxyl 40 stearate, poloxamer, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac and other carriers;

[0038] 3. Combination matrix: take g or kg as the unit, by weight, choose polyethylene glycol, polyoxyl 40 stearate, sodium carboxymethyl starch, beta cyclodextrin, Tween and other carriers for combination test;

[0039] 3.1 The combination of two different subs...

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Abstract

The invention provides a compound drop pill of Chinese yew for the auxiliary treatment of lung carcinoma, which has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, easy administration, low price, and causing no pollution during production. The drop pill is prepared from Chinese yew, red ginseng, licorice root and medicinal carrying agent as the base material.

Description

technical field [0001] The invention relates to a pharmaceutical composition with the function of dispelling pathogenic factors and dispelling stagnation, which is used for adjuvant chemotherapy of middle and advanced lung cancer caused by qi deficiency and phlegm stasis, in particular to a medicinal composition containing three active ingredients of traditional Chinese medicines such as yew, red ginseng and licorice. An oral pharmaceutical preparation prepared from the extract. Background technique [0002] The compound yew capsule prepared according to the preparation method given in the national drug standard WS-10935 (ZD-0935)-2002 is a kind of compound yew capsule with the function of dispelling evil and dispelling stagnation, and is used for middle and advanced lung cancer caused by qi deficiency and phlegm stasis. Oral capsules for the adjuvant treatment of chemotherapy have been clinically verified for many years and have definite curative effects. They are commonly ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/484A61K9/20A61P35/00
Inventor 曲韵智张宝文
Owner 北京博智绿洲医药科技有限公司
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