Method for extracting astilbin from engelhardtia leaves

A technology of astilbin and Huangqi, which is applied in the field of preparation of Huangqi leaf extract, can solve the problems of shortening the production cycle, low yield of astilbin, and low content of active ingredients, so as to shorten the production cycle and avoid the loss of active ingredients , Improve the effect of production process

Active Publication Date: 2006-02-15
GUILIN NATURAL INGREDIENTS CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The technical problem to be solved in the present invention is to overcome the defects in the prior art that the yield of astilbin from the leaves of Huangqi is low, and the content of active ingredients in astilbin is not high, and contains more impurities, and to provide a kind

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] 1) Pre-treatment: crushing the fresh yellow barley leaves;

[0026] 2) Extraction: Mix the raw materials and deionized water in a ratio of 1:3 and put them into the extraction tank, heat to boil and keep the temperature for 2 hours, collect the first extraction material liquid, and add 3 times the amount of deionized water for the second extraction water, heat to boil and keep warm for 2 hours, and collect the second extraction material liquid.

[0027] 3) Concentration under reduced pressure: the extract is introduced into a concentrator for concentration under reduced pressure, the temperature is controlled below 60 degrees Celsius, and the degree of vacuum is controlled above 0.06 MPa.

[0028] 4) Centrifugation: the concentrated extract is centrifuged by a centrifuge.

[0029] 5) The concentrated and centrifuged extract is directly fed into the macroporous resin column; the macroporous resin column is DIAION brand, model D130.

[0030] 6) Wash the column with wate...

Embodiment 2

[0036] 1) Pre-treatment: crushing the dried Huangqi leaves after sorting and removing impurities.

[0037] 2) Extraction: put qualified raw materials into a clean extraction tank, add 10 times the amount of 65% (v / v) ethanol, and extract for the first time under reflux for 2 hours, count the time from the boiling of the solvent, control the temperature at 80°C, and keep it warm until the time is up. Squeeze out the liquid medicine, then add 8 times the amount of 65% (v / v) ethanol for reflux extraction for 3 hours for the second time, and combine the filtrates;

[0038] 3) Recovery of ethanol: pump the extracted medicinal solution into a concentration tank for concentration under reduced pressure and recovery of ethanol, the temperature is controlled below 60°C, and the vacuum degree is controlled above 0.06Mpa. After recovering until there is no alcohol smell, the medicine is hydraulically injected into the liquid storage tank;

[0039] 4) Add water, let it stand, and cool it...

Embodiment 3

[0047] 1) Pre-treatment: crushing the dried and fresh Huang Qi leaves after sorting and removing impurities.

[0048] 2) Extraction: Mix qualified raw materials with ethanol with a weight concentration of 70% in a ratio of 1:8, and perform ultrasonic extraction. The extraction conditions are working frequency 60 kHz, time 90 min, and extraction 2 times;

[0049] 3) Recovery of ethanol: pump the extracted medicinal solution into a concentration tank for concentration under reduced pressure and recovery of ethanol, the temperature is controlled below 60°C, and the vacuum degree is controlled above 0.06Mpa. After recovering until there is no alcohol smell, the medicine is hydraulically injected into the liquid storage tank;

[0050] 4) Add water, let it stand, and cool it down: the ratio of the medicinal solution to the raw material for recovering ethanol should be controlled at about 1:4, if it is not enough, add water, let it stand still, and cool it down;

[0051] 5) Centrifu...

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PUM

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Abstract

The invention provides a process for extracting astilbin from leaves of Engelhardtia roxburghiana wall, which consists of extracting with dissolvent, concentrating, disintegrating and purifying, crystallizing and drying, wherein the dissolvent can employ water or low carbon alcohols such as methanol, ethanol, propanol, isopropyl alcohol, butanol and amylic alcohol.

Description

technical field [0001] The present invention relates to a preparation method of Huang Qi leaf extract, in particular to a method for extracting astilbin from Huang Qi leaves. Background technique [0002] Huang Qiye is the dried leaf of Huang Qi, a plant of the Juglandaceae family. This plant is distributed in Guangdong, Guangxi, Yunnan and other provinces. It is rich in resources and has the effect of clearing away heat and relieving pain. It is used to treat colds, fever, and abdominal pain due to hernia. It is often used as tea in the folks, which can prevent high blood pressure and lower blood lipids. Chemical components such as astilbin are isolated from this plant or plants of the same genus, which have anti-cancer effects. Studies have also shown that astilbin also plays an important role in the body's anti-rejection: astilbin can induce apoptosis of T lymphocytes activated by phytohemagglutinin, and can induce apoptosis of activated T cells infiltrated around the hep...

Claims

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Application Information

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IPC IPC(8): C07J63/00
Inventor 宋云飞季永贤孙步祥梁远盛汤凌志李杰
Owner GUILIN NATURAL INGREDIENTS CORP
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