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Zhimiling preparation and its making method thereof

A preparation and formula technology, applied in the field of Zhimiling preparation and its preparation, can solve the problems of single dosage form and inconvenient storage of suppositories

Inactive Publication Date: 2006-03-15
毛友昌
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Suppository is a commonly used vaginal dosage form, but it is inconvenient to store and requires storage below 30°C, and its use in some high-temperature and alpine regions is subject to certain restrictions. At the same time, the dosage form is single

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Take 25 grams of Phellodendron cortex, 25 grams of Sophora flavescens, 25 grams of catechu, 20 grams of dry alum, and 5 grams of borneol.

[0028] The five kinds of medicines are inspected separately and used for later use; the catechu and dried alum are crushed into fine powder, and the borneol is finely ground for later use. Take Phellodendron Phellodendron and Kushen and boil them in water for three times, 2, 1, and 1 hour in turn, combine the decoctions, filter, concentrate the filtrate to an appropriate amount, add ethanol to make the alcohol content 75%, let it stand for precipitation, and take the supernatant Recover ethanol, concentrate, dry, pulverize into fine powder, and mix with the above-mentioned fine powder such as dried alum for later use; take an appropriate amount of Vaseline, heat and melt, and the temperature drops to about 50°C, add an appropriate amount of liquid paraffin and Tween-80, and prepare a matrix , first add the above-mentioned standbys, ...

Embodiment 2

[0030] Take 8 grams of Phellodendron cortex, 8 grams of Sophora flavescens, 8 grams of catechu, 6 grams of dry alum, and 1.5 grams of borneol.

[0031] The five kinds of medicines are inspected separately and used for later use; the catechu and dried alum are crushed into fine powder, and the borneol is finely ground for later use. Take Phellodendron Phellodendron and Kushen and boil them in water for three times, 2, 1, and 1 hour in turn, combine the decoctions, filter, concentrate the filtrate to an appropriate amount, add ethanol to make the alcohol content 75%, let it stand for precipitation, and take the supernatant Recover ethanol, concentrate, dry, crush into fine powder, mix with the above fine powder such as dry alum, add an appropriate amount of liquid paraffin and stir well for later use; take another appropriate amount of Vaseline and lecithin, heat and melt, and the temperature drops to about 50 °C, add the above The spare parts are fully stirred, compressed into ...

Embodiment 3

[0033] Take 80 grams of Phellodendron cortex, 80 grams of Sophora flavescens, 80 grams of catechu, 60 grams of dry alum, and 15 grams of borneol.

[0034] The five kinds of medicines are inspected separately and used for later use; the catechu and dried alum are crushed into fine powder, and the borneol is finely ground for later use. Take Cortex Cortex Phellodendron and bitter ginseng and decoct in water for three times, 2, 1, and 1 hour in turn, combine the decoction, filter, concentrate the filtrate, dry, pulverize into fine powder, mix with the above fine powder such as dry alum and appropriate amount of auxiliary materials, pack 50 capsules, packaged, that is Zhimiling Capsules.

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PUM

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Abstract

A Chinese medicine 'Zhimiling' in the form of tablet, disintegrating tablet, effervescent tablet, or soft-gel-type suppository for treating cervical erosion and vaginitis is prepared from phellodendron bark, flavescent sophora root, catechu, baked alum, borneol and additive. Its advantages are high curative effect, broad spectrum, and no irritation.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, in particular to a preparation for treating miling and a preparation method thereof. Background technique [0002] Uterine erosion, vaginitis, etc. are women's common and frequently-occurring diseases. Bring a lot of misery to the patient, have a strong impact on the health of women in general. Zhimiling preparation is composed of Phellodendron Phellodendron, Sophora flavescens, catechu, dried alum, and borneol. It has the functions of clearing away heat and dampness, detoxification and anti-inflammation, removing putrefaction and promoting muscle growth. It is used for cervical erosion, infectious vaginitis, and trichomoniasis vagina Inflammation and other diseases have a significant effect. At present, there is Zhimiling Suppository, which has been listed in Volume 11 of the Ministry of Health Drug Standards of the People's Republic of China "Prescriptions of Traditional Chinese Medicine". S...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K31/045A61K33/06A61K9/00A61P15/02A61P15/00
Inventor 毛友昌毛晓敏
Owner 毛友昌
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