Prepn process of malaytea scurfpea injection

Abstract

The preparation process of malaytea scurfpea injection includes the following steps: eliminating impurity from malaytea scurfpea fruit as material, crushing into coarse powder, ultrasonic extraction in 75 % concentration alcohol solution for 2-4 times of 1-2 hr each to obtain the extracted liquid, decompression concentration to obtain dense paste while recovering alcohol, diluting with 0.85 % concentration sodium chloride solution via stirring, letting stand and taking supernatant, regulating pH to 3.0 with hydrochloric acid, cold storing, regulating pH to 6.5-7.5, filtering, filling, sterilizing and packing the malaytea scurfpea injection. The malaytea scurfpea injection is used in intramuscular injection to treat leucoderma and psoriasis and can heal leucoderma and psoriasis radically.

Description

Technical field: [0001] The invention relates to a preparation method of an injection, in particular to a preparation method of a psoralen injection obtained by extracting psoralen and isopsoralen from psoralen raw materials. Background technique: [0002] With the acceleration of the pace of modern life, the increase of work pressure and the destruction of the environment by industrialized production, the function of the human immune system is reduced, and the incidence of various diseases is on the rise. Persistent skin diseases that have plagued and tortured human beings for thousands of years, such as vitiligo Skin diseases such as psoriasis and psoriasis are also on the rise. [0003] Psoriasis, also known as psoriasis, is a common chronic inflammatory skin disease with intractable and relapsing characteristics. It has obvious seasonality, and the condition of most patients is aggravated in spring and winter, and relieved in summer. The national total prevalence rate ...

AI Technical Summary

Problems solved by technology

[0006] At present, the extraction of psoraleae medicinal materials mostly adopts the process of water extraction and alcohol precipitation or alcohol extraction and water precipitation, and the more advanced ones are supercritical CO 2 Extraction, which has high extraction efficiency, little change in active ingredients, and better extraction, separation, and concentration effects, is technically the preferred extraction process, but the investment in the equipment used in this extraction process is too large at one time. In the absence of readily available supercritical CO 2 Extraction line is difficult to do, subject to certain limitations; the use of enzyme extraction, the yield is also high, and easy to operate, but the enzyme preparation is difficult to buy, and the cost is too high; percolation and Soxhlet extraction product impurities are relatively low Therefore, it is necessary to develop a new extraction process for psoralen injection