Compound black-bone chicken tablet, its preparing method and quality control method

A technology of black-bone chicken slices and black-bone chicken, which is applied in the directions of pill delivery, measuring device, pharmaceutical formulation, etc., can solve the problems of inconvenience in carrying and transportation, large amount of auxiliary materials, low preparation quality control standards, etc. The effect of broad market potential

Inactive Publication Date: 2006-08-09
毛晓敏
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The main problems existing in the prior art are: (1) the oral liquid is unstable, and it is easy to produce precipitation for a long time, and the production cost is high, and it is inconvenient to carry and transport; ) Existing dosage forms all have the deficiency of high sugar content, are not suitable for diabetics, patients with liver disease, etc. to take, and for normal people, excessive intake of sugar will cause damage to the human body, leading to obesity, high blood pressure, heart disease, diabetes (4) Although the existing dosage forms have added flavoring agents such as sugar and honey for flavoring, the mouthfeel is still not very satisfactory; (5) the quality control standard of the existing preparations is relatively low

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0080] Embodiment 1: the extraction of yam, Radix Astragali, Radix Codonopsis, Poria cocos

[0081] Yam, Astragalus, Codonopsis, and Poria are extracted by water extraction and alcohol precipitation technology. While extracting active ingredients, it can effectively reduce the yield of ointment and reduce the introduction of ineffective ingredients such as starch.

[0082]The main factors affecting the effect of water extraction are the crushing degree of medicinal materials, the amount of water added, the decoction time, the number of decoctions and the soaking time. The soaking of medicinal materials before decoction has a certain influence on the decoction effect. The soaking time before decoction should be based on the soaking time of medicinal materials. Poria cocos and yam are not easy to soak in among these four herbs, so Poria cocos and yam fragments should be selected without hard core. After adding water, soak for 0.5, 1, and 2 hours to observe, take out the poria co...

Embodiment 2

[0084] Embodiment 2: the extraction of black-bone chicken

[0085] Egg white can be hydrolyzed by acid to become peptides and amino acids that are more easily absorbed and utilized by the human body. The main factors affecting acid hydrolysis are acid type, acid concentration and dosage, concentration and time of heating hydrolysis. Taking the nitrogen content of black-bone chicken hydrolyzed powder as the investigation index, the useful amount of dilute sulfuric acid was determined. The experiments and results are shown in Table 2. It can be seen from Table 2 that the ratio of black-bone chicken weight to dilute sulfuric acid is 1:1.2 is better.

[0086] Test No.

[0087] 6

Embodiment 3

[0088] Example 3: Extraction of Rehmannia glutinosa, Atractylodes macrocephala, Radix Paeoniae Alba, Cortex Moutan, Rhizoma Chuanxiong, Angelica sinensis and Schisandra chinensis

[0089] Rehmannia glutinosa, Atractylodes macrocephala, Radix Paeoniae Alba, Cortex Moutan, Rhizoma Chuanxiong, Angelica sinensis and Schisandra chinensis were infiltrated with ethanol at an appropriate concentration. The main factors affecting percolation were the crushing degree of the medicinal materials, the concentration and dosage of ethanol, and the rate of flow. According to experience, the flow rate can usually be fixed at 3-5ml / kg·min. The amount of percolation is collected with the end point of percolation until colorless. The key to percolation effect is the alcohol concentration. The concentration of ethanol is determined by the yield of extract and the amount of paeoniflorin, the active ingredient in Atractylodes macrocephala and Radix Paeoniae Alba. The tests and results are shown in T...

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PUM

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Abstract

The invention relates to a Chinese medicinal preparation-compound black-bone chicken tablet having functions of tonifying Qi and blood and benefitting kidney and liver, and the preparing and quality control methods thereof. It has many advantages of stability, being convenient to take and carry, no sugar, no bad smell, suitable to industrialized production, low production cost, etc, and simultaneously provides the preparing and quality control methods, which comprises identifying White Paeony Root, cortex moutan radicis, Milkvetch Root, Radix Codonopsis, Chinese Angelica and Rhizoma Chuanxiong in the black-bone chicken tablet, determining the content of active substance of White Paeony Root and cortex moutan radicis- paeoniflorin in the black-bone chicken tablet, and controlling total nitrogen content in the black-bone chicken tablet.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a compound black-bone chicken tablet, and at the same time relates to a preparation method of the preparation and a quality control method. Background technique [0002] Irregular menstruation due to qi and blood deficiency or liver and kidney deficiency, gynecological diseases such as spleen deficiency or kidney deficiency are common and frequently-occurring diseases in clinical practice. In traditional Chinese medicine, methods such as nourishing qi and blood and nourishing liver and kidney are often used for treatment. It is of great significance to carry forward the traditional advantages of traditional Chinese medicine and develop traditional Chinese medicine preparations that are stable, safe to use, accurate in dosage, controllable in quality, and reliable in efficacy. [0003] The prescription of "Compound Black-bone Chicken Tablets" comes from the ministry st...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61K35/12A61K9/20A61P1/14A61P15/00G01N30/90G01N33/15A61K35/57
Inventor 毛晓敏
Owner 毛晓敏
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