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Vaginal capsule suppository for female

A technology of Baofukang and capsules, which is applied in the directions of capsule delivery, suppository delivery, and medical preparations containing active ingredients to achieve the effect of safe and effective use and reduced damage.

Inactive Publication Date: 2006-10-11
孙红卫 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The purpose of the present invention is to solve the problems existing in the existing Baofukang suppository by utilizing the characteristics of large drug loading, small volume, simple process, easy realization of industrialized large-scale production, transportation, storage and use of soft capsules or hard capsules, Prepare a capsule for vaginal use of Baofukang, prepare low-dose and high-dose preparations at the same time, expand the application range of the original preparation, and better play the role of "Baofukang" in fungal vaginitis, senile vaginitis, and cervical erosion therapeutic effect in

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] Curcuma Oil 82g

[0049] ice flakes 75g

[0050] Liquid paraffin 270g

[0051] White Vaseline 30g

[0052] Beeswax 10g

[0053] Soy Lecithin 23g

[0054] Lauric acid 10g

[0055] Made into 1000 grains (0.5g / grain)

[0056] 1. Weigh the prescribed amount of borneol, add 200g of liquid paraffin, heat to dissolve, and set aside.

[0057] 2. Weigh the prescribed amount of zedoary oil, vaseline, beeswax, lauric acid and the remaining liquid paraffin, heat and dissolve at 75°C until clear. Add the prescribed amount of soybean lecithin, stir, mix evenly, and set aside.

[0058] 3. Add the above 1 to 2, mix, pass through a colloid mill to mix evenly, and when the temperature drops to 20-35°C, make it fluid, and set aside.

[0059] 4. Fill the fluid of "3" directly into hard capsules to prepare Baofukang hard capsules for vaginal use. If you need to prepare soft capsules, you need to proceed to the next step.

[0060] 5. Preparation of ...

Embodiment 2

[0064] Curcuma Oil 82g

[0065] ice flakes 75g

[0066] Yellow Vaseline 10g

[0067] Monoglycerides 3g

[0068] Span-80 20g

[0069] Stearic acid 7g

[0070] Liquid paraffin 300g

[0071] Made into 1000 grains (0.5g / grain)

[0072] 1. Take the prescribed amount of borneol, add 200g of liquid paraffin, heat to dissolve, and set aside.

[0073] 2. Weigh the prescribed amount of zedoary oil, vaseline, monoglyceride, Span-80, stearic acid and the rest of the liquid paraffin, heat and dissolve at 80°C until clear. spare.

[0074] 3. Add the above 1 to 2, mix, pass through a colloid mill to mix evenly, and when the temperature drops to 20-35°C, make it into a thin fluid paste for later use.

[0075] 4. Fill the fluid of "3" directly into hard capsules to prepare Baofukang hard capsules for vaginal use. If you need to prepare soft capsules, you need to proceed to the next step.

[0076] 5. Preparation of glue: mix gelatin-glycerin-water in a...

Embodiment 3

[0080] Curcuma Oil 82g

[0081]ice flakes 75g

[0082] White Vaseline 10g

[0083] Monoglycerides 3g

[0084] Span-80 20g

[0085] Stearic acid 7g

[0086] Liquid paraffin 300g

[0087] Made into 1000 grains (0.5g / grain)

[0088] 1. Take the prescribed amount of borneol, add 200g of liquid paraffin, heat to dissolve, and set aside.

[0089] 2. Weigh the prescribed amount of zedoary oil, vaseline, monoglyceride, Span-80, stearic acid and the rest of the liquid paraffin, heat and dissolve at 80°C until clear. spare.

[0090] 3. Add the above 1 to 2, mix, pass through a colloid mill to mix evenly, and when the temperature drops to 20-35°C, make it into a thin fluid paste for later use.

[0091] 4. Fill the fluid of "3" directly into hard capsules to prepare Baofukang hard capsules for vaginal use. If you need to prepare soft capsules, you need to proceed to the next step.

[0092] 5. Preparation of glue: mix gelatin-glycerin-water in a ratio...

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Abstract

The invention relates to a capsule for treating women's vaginal diseases, as well as the preparing process, wherein the capsule comprises contents and hard shells, the contents include oil of aromatic turmeric, borneo camphor and auxiliary materials.

Description

Technical field: [0001] The invention belongs to the reform of dosage forms and drug proportions of Baofukang suppositories, in particular Baofukang capsules and a preparation method thereof. Background technique: [0002] Baofukang suppository is a variety recorded in the first part of the Chinese Pharmacopoeia 2000 edition. Its composition is: turmeric oil 82g, borneol 75g, the preparation method is: the above two flavors, mix zedoary oil with 75g polysorbate 80, and use Appropriate amount of ethanol is dissolved and mixed with the above oil solution evenly. Separately take 1551g of polyoxyethylene stearate, melt it on a water bath, add the above liquid medicine, stir well, pour it into a suppository mold, take it out after cooling, and make 1000 capsules. Appearance: This product is in the shape of milky white, milky yellow or brown bullet. This product promotes the circulation of qi and removes blood stasis, promotes granulation, and relieves pain. For fungal vaginiti...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/02A61K9/48A61K31/045A61P15/02
Inventor 孙红卫张建伟
Owner 孙红卫
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