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Agricultural bactericide containing camptothecin or camptothecin derivative and application thereof

An agricultural fungicide, camptothecin technology, applied in the direction of fungicides, biocides, chemicals for biological control, etc., can solve the problems of insoluble, low practicability and so on

Inactive Publication Date: 2006-12-27
YIFAN AGRI CHEM PLANT ZHEJIANG PROV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the above-mentioned alkaloids are all natural alkaloids, and are difficult to dissolve in water, especially camptothecin, the enforceability of this patent is relatively small
And the report that camptothecin or camptothecin derivative is applied in crop fungicide has never seen

Method used

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  • Agricultural bactericide containing camptothecin or camptothecin derivative and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] 1) Put 100L ethanol into the reaction kettle or stirring tank, add 60L calcium dodecylbenzenesulfonate, after stirring, add 40L OP-10, stir evenly, that is, the compound emulsifier, set aside;

[0023] 2) Put 400L dimethyl sulfoxide into another reaction kettle or stirring tank, add 0.5kg of camptothecin with a purity of 90%, heat to 35°C and keep stirring, after the camptothecin is completely dissolved, add the above compound 20L of emulsifier, after stirring evenly, add 15L of JFC and 5L of azone, and stir evenly to obtain the final product.

Embodiment 2

[0025] 1) Put 100L ethanol into the reaction kettle or stirring tank, add 60L calcium dodecylbenzenesulfonate, after stirring, add 40L OP-10, stir evenly, that is, the compound emulsifier, set aside;

[0026] 2) Put 400L of mixed solvent (methanol+ethanol, 1:1) into another reaction kettle or stirring tank, add 0.2kg of 10-hydroxycamptothecin with a purity greater than 90%, stir and dissolve completely, then add 1.8kg of 10-hydroxycamptothecin with a purity greater than 90% % above fipronil, after stirring and dissolving, add 30L Tween-80 and stir evenly, add 10L JFC and 1L azone, stir evenly to obtain the final product.

Embodiment 3

[0028] 1) Put 100L dimethylformamide into the reaction kettle or stirring tank, add 40L calcium dodecylbenzenesulfonate, after stirring, add 30L OP-10 and 30L Tween-80 and stir evenly, that is, the compound emulsifier, spare;

[0029] 2) drop into 400L dimethyl sulfoxide in another reactor or stirring tank, add 0.3kg purity and be 90% camptothecin and 0.2kg purity be 90% 10-hydroxycamptothecin, be heated to 35 ℃ and Stir constantly, after completely dissolving, add 20L of the above-mentioned compound emulsifier, after stirring evenly, add 5L of JFC and 2L of azone, stir evenly, and obtain the final product.

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Abstract

Disclosed is the agricultural pesticide containing camptothecine or camptothecine derivatives and the use thereof, wherein the pesticide comprises camptothecine or its derivatives 0.02-2.0%, emulsifying agent 1.0-20%,penetrating agent 0.5-10%, and balancing organic solvent. The pesticide can be used for controlling agronomic crop downy mildew, leaf streak, pythium blight, head blight, root and stem rot, rhizoctonia rot, damping-off, wilt,bitter rot, powdery mildew, black shank, brown spot, leaf scab, ring rot, black pox, gray mold,phytophthora rot, ulcer disease, black spot, bacterial wilt, angular leaf spot, leaf streak and leaf scar.

Description

technical field [0001] The invention belongs to the technical field of botanical fungicides, in particular to agricultural fungicides containing camptothecin or camptothecin derivatives and applications thereof. Background technique [0002] Camptothecin (hydroxycamptothecin) is a pyrroloquinoline alkaloid, and the general chemical structure formula of camptothecin and its derivatives is as general formula (I): [0003] [0004] General formula (I) [0005] Among them, R1——10 in the chemical structure represent hydrogen atom, methyl group, ethyl group, propyl group, butyl group, hydroxyl group, nitro group, amino group, oxymethyl group, methylaminooxy group, fluoroethyl group, chloroethyl group , one of bromoethyl, nitrogen, silyl, and alkoxy. Camptothecin is mainly derived from the unique plant Camptotheca involucrata in my country. In 1966, Wall et al. isolated it for the first time from Camptothecus intr...

Claims

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Application Information

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IPC IPC(8): A01N43/90A01P3/00
Inventor 张立钦马建义马良进王品维刘兴泉毛胜凤
Owner YIFAN AGRI CHEM PLANT ZHEJIANG PROV
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