Medical composite prepared by Gynostemma pentaphylla, American ginseng and astragalus root

A composition and a technology of American ginseng, applied in the field of medicine, can solve problems such as unseen tumors

Inactive Publication Date: 2007-05-02
海安江理工技术转移中心有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, there is no report on the combination of Gynost

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0181] Example 1 Preparation of Gypenosides

[0182] Take the Gynostemma pentaphyllum medicinal material, add 75% ethanol and reflux for extraction twice, 2 hours each time, filter, and recover the ethanol from the stream until it has no alcohol taste. Add water to make a solution equivalent to 2g crude drug per 1ml, stir well, let cool, and let it stand still. Leave it overnight, filter, and pass the filtrate through the processed macroporous resin column. First wash the column with 2 times the column volume of water, discard the water, and then use 3 times the column volume of 60% ethanol for elution, and collect the elution. Liquid, recover ethanol, concentrate to a concentrated liquid with a relative density of 1.08-1.10, spray dry, and get it.

[0183] Three batches of total gypenosides were prepared, and the yield and content of the extracts are shown in Table 10.

[0184] Assay

[0185] Preparation of reference substance solution Accurately weigh an appropriate amount of Gy...

Example Embodiment

[0191] Example 2 Preparation of Panax quinquefolium saponins

[0192] Take American ginseng, add 10 times the amount of water, soak for 8 hours, filter out the soaking liquid, add 8 times the amount of normal water, decoct for 1 hour, a total of two times, combine the extracts, concentrate under reduced pressure to a density of 1.19~1.25 ( 60), spray drying, get water extract powder. Add 8, 5, 5, and 5 times the amount of n-butanol successively, and extract with boiling water bath for 1 hour, a total of 4 times, combine the extracts, recover the n-butanol under reduced pressure, and vacuum dry to obtain crude total saponins. Stir the crude total saponins into 20 times the amount (W / W) D 101 Type macroporous resin, rinse with hot water until the washing water is almost colorless, stir and elute with 4 times the amount of 80% ethanol for two times, each time for 1 hour, combine the eluates, recover the n-butanol under reduced pressure, and spray dry to obtain .

[0193] Identificati...

Example Embodiment

[0209] Example 3 Preparation of Astragalus Polysaccharide

[0210] Take astragalus medicinal materials, add 7 times the amount of 70% ethanol to extract twice, 2 hours each time, discard the extract, take the medicinal residue and add water to extract twice, combine the extracts and concentrate until the ratio of the volume of the extract to the crude medicinal material is 1.05: 1. Add ethanol to precipitate to make the alcohol content reach 70%, filter to obtain the precipitate, wash the precipitate with 70% ethanol, then dissolve it with an appropriate amount of water, filter, the filtrate is over the macroporous resin, eluted with water, collect the washing liquid, and wash the liquid Concentrate to a ratio of 1:2.5 between the volume of the medicinal solution and the medicinal materials. Add ethanol to make the alcohol content reach 70% to obtain a precipitate. The precipitate is washed and dehydrated with 95% ethanol and acetone, and dried under reduced pressure (60°C) to obt...

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PUM

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Abstract

A composite medicine for preventing and treating primary liver cancer, lung cancer, rectum cancer, lymph cancer, gynecologic cancers, etc is proportionally prepared from gynostemma pentaphyllum or its extract, American ginseng or its extract, and astragalus root or its extract. Its preparing process is also disclosed.

Description

1. Technical field [0001] The present invention relates to a pharmaceutical composition with anti-tumor effect, in particular to a pharmaceutical composition composed of Gynostemma or Gynostemma extract, American ginseng or American ginseng extract, Radix Astragali or Radix Astragali extract and a preparation method thereof, and a pharmaceutical composition containing the drug The preparation of the composition belongs to the technical field of medicine. 2. Background technology [0002] Since the 1970s, the incidence and mortality of cancer in my country have been on the rise. In the 20 years to the 1990s, the cancer mortality rate increased by 29.42%, and the age-adjusted mortality rate increased by 11.56%. In 2000, the incidence of cancer was about 1.8 to 2 million, and the death toll was 1.4 to 1.5 million. Cancer is becoming the number one killer of human beings in the new century. At present, the treatment of cancer in modern medicine is mainly surgical treatment comb...

Claims

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Application Information

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IPC IPC(8): A61K36/481A61P35/00
Inventor 黄振华
Owner 海安江理工技术转移中心有限公司
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