Polymeric marker with high radiopacity

a polymer marker and radiopacity technology, applied in the direction of radiation diagnostic clinical applications, prosthesis, discharge tube/lamp details, etc., can solve the problems of catheter shaft, undesirable discontinuity, and relatively expensive manufacture of metallic markers

Inactive Publication Date: 2005-03-24
ABBOTT CARDIOVASCULAR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0008] The present invention overcomes the shortcomings of previously described polymeric radiopaque markers by enabling a polymer to be filled or doped with a considerably greater quantity of a radiopaque agent than has heretofore been achievable. The increased fill ratio nonetheless allows uniform pellets to be compounded and ...

Problems solved by technology

Such configuration, however, locally stiffens the catheter shaft and thereby imparts an undesirable discontinuity thereto as the solid metal bands are relatively inflexible compa...

Method used

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  • Polymeric marker with high radiopacity
  • Polymeric marker with high radiopacity

Examples

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Embodiment Construction

[0017] The present invention provides a radiopaque marker for use on a variety of devices that is flexible, highly radiopaque and is easily attachable to such devices by melt bonding. These properties allow markers to be of minimal thickness and thereby minimize the effect the marker has on the overall profile and stiffness of the device to which it is to be attached.

[0018] In order to achieve the high fill ratios that are necessary to attain the desired radiopacity and in order to do so without compromising the compoundability and workability of the polymeric material nor its ultimate strength and flexibility, a number of different parameters have been found to be of importance. More specifically, both the particle shape and particle size of the radiopaque agent must be carefully controlled while the inclusion of a MA-g-PO in the polymer blend is critical. An antioxidant may additionally be included in an effort to reduce the adverse effect the high processing temperatures and she...

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Abstract

High radiopacity is achieved in a polymeric marker by combining a polymeric resin, a powdered radiopaque agent having uniformly shaped particles of a specific particle size distribution and a vetting agent. The method to produce the marker calls for the blending and pelletization of these materials followed by extrusion onto support beading. The resulting supported tubing is subsequently cut to length with the beading still in place. After ejection of the beading remnant the marker is slipped into place on the device to be marked and attached by melt bonding. Marking of a guidewire allows lesions to be measured while the marking of balloon catheters allow the balloon to be properly positioned relative to a lesion.

Description

BACKGROUND OF THE INVENTION [0001] The present invention is directed to elongated intracorporeal devices, and more particularly intraluminal devices for stent deployment, percutaneous transluminal coronary angioplasty (PTCA), and the similar procedures. PTCA is a widely used procedure for the treatment of coronary heart disease. In this procedure, a balloon dilatation catheter is advanced into the patient's coronary artery and the balloon on the catheter is inflated within the stenotic region of the patient's artery to open up the arterial passageway and increase the blood flow through the artery. To facilitate the advancement of the dilatation catheter into the patient's coronary artery, a guiding catheter having a preshaped distal tip is first percutaneously introduced into the cardiovascular system of a patient by the Seldinger technique through the brachial or femoral arteries. The catheter is advanced therein until the preshaped distal tip of the guiding catheter is disposed wi...

Claims

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Application Information

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IPC IPC(8): A61B5/107A61B19/00A61F2/06A61F2/84A61L29/18A61L31/18A61M25/01
CPCA61B5/1076Y10T428/139A61F2/958A61F2250/0098A61L29/18A61L31/18A61M25/0108A61B6/485A61B6/12A61B5/6853A61B5/6851A61M25/09A61M25/0012A61L31/125A61M25/1027Y10T428/12493Y10T156/1089Y10T428/1372A61B19/54A61B90/39A61B2562/17
Inventor BAVARO, VINCENT PETERSIMPSON, JOHN ARTHURD'AQUANNI, PETERBALDWIN, AARON
Owner ABBOTT CARDIOVASCULAR
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