The invention discloses a non-pneumatic tire material taking thermoplastic vulcanized rubber as a base material and a preparation method of the non-pneumatic tire material, and belongs to the field ofmodified polymer materials and non-pneumatic tires. The material mainly comprises thermoplastic vulcanized rubber, a styrene elastomer, a hydrogenated styrene elastomer, a plasticizer, polypropylene,polyethylene, a filler, a hyperbranched polymer, a compatilizer, an antioxidant, a wear-resistant anti-slip agent and an ultraviolet light absorber. The preparation method comprises the following steps: mixing and stirring the thermoplastic vulcanized rubber, the styrene elastomer, the hydrogenated styrene elastomer and the plasticizer, mixing the rest materials, and carrying out melt mixing to obtain the target product. The non-pneumatic tire material prepared by the preparation method has the advantages of wear resistance, skid resistance, fatigue resistance, high toughness, high elasticity, low possibility of compressive deformation and the like, can effectively reduce the safety risks of air leakage, tire burst and the like in the driving process of a vehicle, can be recycled, and hasthe characteristics of greenness and environmental protection.