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Method of treating skin with a composition comprising a phosphoric triester and a skin activating component

a technology of phosphoric triester and skin activating component, which is applied in the field of cosmetics, can solve the problems of skin delicately affected by aging, skin and aging of the skin, and cutaneous troubles, and achieve the effects of preventing and remedying skin roughness, enhancing the effect and facilitating the penetration of skin activating componen

Inactive Publication Date: 2005-06-09
KAO CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0009] In view of the foregoing circumstances, the present inventors have carried out an extensive investigation. As a result, it has been found that when a specific phosphoric triester and a skin activating component are used in combination, the phosphoric triester facilitates the penetration of the skin activating component to synergistically enhance the effects of the skin activating component, i.e., the moisturizing effect, the effects of preventing and remedying skin roughness, the effects of preventing the firm and resilient skin from declining and remedying the declined skin, the effects of preventing a complexion from dulling and remedying a dull looking face, the effects of preventing and remedying the conspicuousness of pores of the skin and pimples caused by excess sebum, microorganisms or keratonosis, the effects of preventing development of wrinkles and remedying the wrinkled skin, the effects of preventing and remedying spots and freckles, the effects of preventing and remedying the conspicuousness of pores of the skin and pimples caused by excess sebum, and the effects of preventing development of wrinkles and remedying the wrinkled skin, and so a cosmetic which can effectively remedy the above-described cutaneous troubles and gives users a pleasant feeling upon use is provided, thus leading to completion of the present invention.
[0013] According to the present invention, there is also provided a method for improving the efficacy of a skin activating component, which comprises incorporating a phosphoric triester of the general formula (1) into a cosmetic composition comprising the skin activating component.

Problems solved by technology

However, the skin is delicately affected by aging, and besides temperature, humidity, ultraviolet rays, cosmetic products, diseases, stress, eating habits, etc.
Therefore, various troubles such as the decrement of various functions (functions of preventing the loss of water and the like from the vital body to control the homeostatic maintenance of the body heat, protecting the body from physical and chemical stimulation and various bacteria and keeping the resilience of the skin to determine its surface form, and the like) of the skin and aging of the skin occur.
Further, the cutaneous troubles occur due to, in addition to the functional aberration of skin tissue caused by intracorporeal and extracorporeal factors, which act on the vital body, such as changes of the external environments (seasonal changes, ultraviolet rays, etc.) and variations in physiological functions attendant on aging or diseases as described above, pachymenia, parakeratosis and the like induced thereby.
On the other hand, wrinkles, which are one of dermal troubles, occur due to dermal aging caused by aging, drying, ultraviolet rays and / or the like.
However, all these means have not attained a sufficient effect on the cutaneous troubles.

Method used

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  • Method of treating skin with a composition comprising a phosphoric triester and a skin activating component
  • Method of treating skin with a composition comprising a phosphoric triester and a skin activating component
  • Method of treating skin with a composition comprising a phosphoric triester and a skin activating component

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0083] Cosmetics of their corresponding formulations shown in Tables 1 to 6 were prepared in accordance with a method known per se in the art. The cosmetics thus obtained were used to evaluate them as to the moisturizing effect on the skin, the effects of preventing and remedying skin roughness, the effects of preventing the firm and resilient skin from declining and remedying the declined skin, the effects of preventing a complexion from dulling and remedying a dull looking face, the effects of preventing and remedying the conspicuousness of pores of the skin and pimples caused by excess sebum, microorganisms or keratonosis, the effects of preventing development of wrinkles and remedying the wrinkled skin, the effects of preventing and remedying spots and freckles, and a feeling upon use. The results are shown in Tables 1 to 6.

(Evaluation Method)

[0084] Moisturizing effect on the skin, the effects of preventing and remedying skin roughness, the effects of preventing the firm and ...

example 2

[0096] Cosmetics of their corresponding formulations shown in Table 7 were prepared to determine the retention of their moisturizing effects.

TABLE 7Invention productComparative productComponent (wt. %)89101189101112(1)Bis(butoxyethoxyethyl)-ethyl phosphate5025——100————(2)Tris(butoxyethyl) phosphate——5025—100———(3)Dipropylene glycol50505050——100——(4)Glycerol—25—25———100—(5)Purified water————————100

Testing Method

[0097] A fixed amount of each of the above samples was applied to the lower inner arm of a volunteer and washed off with hot water after left at rest for 1 hour. The volunteer was got to enter an air-conditioned room kept at a temperature of 20° C. and a humidity of 30%. Fifteen minutes after that, the water content in the horny layer of the volunteer was measured by an impedance meter (manufactured by IBS Company). After additional 3 hours, the treated arm was washed with hot water again. Fifty minutes after that, the water content was measured in the same manner as descr...

example 3

[0099] Creams of their corresponding formulations shown in Table 9 were prepared to determine the retention of their moisturizing effects.

TABLE 9InventionComp.productproductComponent (wt. %)121313(1)Vaseline6.06.06.0(2)Cetanol3.03.03.0(3)Lipophilic glycerol2.02.02.0monostearate(4)Polyoxyethylene sorbitan2.02.02.0monoglycerate (20 E.O.)(5)Bis(butoxyethoxyethyl)-20.0——ethyl phosphate(6)Tris(butoxyethyl)—20.0—phosphate(7)Olive oil——20.0(8)Butylparaben0.10.10.1(9)Methylparaben0.10.10.1(10) Dipropylene glycol10.010.010.0(11) Perfume base0.10.10.1(12) Purified waterBalanceBalanceBalance

Preparation Process

[0100] The oil-phase components (1) to (8) were mixed and heated to melt them. The melt was kept at 70° C., while the water-phase components (9) to (12) were gradually added to the melt. The resultant mixture was emulsified by an emulsifier. The emulsion was cooled down to a final temperature of 25° C., thereby preparing a cream.

Testing Method

[0101] A fixed amount of each of the ab...

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Abstract

The invention relates to a cosmetic comprising (A) a phosphoric triester represented by the general formula (1): wherein R1 and R2 are independently an alkyl group having 1 to 8 carbon atoms, R3 is an alkyl group having 1 to 4 carbon atoms, X, Y and Z are independently an alkylene group having 2 or 3 carbon atoms, l and m are independently a number of 1 to 10, and n is a number of 0 to 10, and (B) a skin activating component. The cosmetic is excellent in moisturizing effect; the effects of preventing and remedying skin roughness; the effects of preventing the firm and resilient skin from declining and remedying the declined skin; the effects of preventing a complexion from dulling and remedying a dull looking face; the effects of preventing and remedying the conspicuousness of pores of the skin and pimples caused by excess sebum, microorganisms or keratonosis; the effects of preventing development of wrinkles and remedying the wrinkled skin; and the effects of preventing and remedying spots and freckles, and moreover gives users a pleasant feeling upon use.

Description

TECHNICAL FIELD [0001] The present invention relates to a cosmetic which is excellent in preventing and remedying effects on a variety of cutaneous troubles and gives users a pleasant-feeling upon use. BACKGROUND ART [0002] In recent years, it has been a matter of significant concern to maintain a healthy and beautiful skin irrespective of age or sex. However, the skin is delicately affected by aging, and besides temperature, humidity, ultraviolet rays, cosmetic products, diseases, stress, eating habits, etc. Therefore, various troubles such as the decrement of various functions (functions of preventing the loss of water and the like from the vital body to control the homeostatic maintenance of the body heat, protecting the body from physical and chemical stimulation and various bacteria and keeping the resilience of the skin to determine its surface form, and the like) of the skin and aging of the skin occur. [0003] Further, the cutaneous troubles occur due to, in addition to the f...

Claims

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Application Information

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IPC IPC(8): A61K8/34A61K8/365A61K8/368A61K8/44A61K8/46A61K8/49A61K8/55A61K8/60A61K8/63A61K8/67A61K8/68A61K8/73A61K8/92A61K8/97A61K8/98A61Q19/00A61Q19/02A61Q19/08
CPCA61K8/342A61Q19/08A61K8/365A61K8/466A61K8/55A61K8/63A61K8/675A61K8/676A61K8/678A61K8/68A61K8/73A61K8/922A61K8/97A61K8/988A61Q19/00A61Q19/02A61K8/347A61K8/9711A61K8/9717A61K8/9741A61K8/9761A61K8/9767A61K8/9771A61K8/9789A61K8/9794A61P17/00A61P17/16
Inventor ISHIKAWA, SHINJITANAHASHI, MASANORISANO, TOMOHIKOSUGAI, ICHIRO
Owner KAO CORP
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