Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto

a technology which is applied in the field of aryl and heteroaryl derivatives, can solve the problems of elevated blood glucose levels, serious health problems, and inability to move glucose into the cells of the individual, and achieve the effect of reducing the weight gain of the individual
US20070072844A1Inactive Publication Date: 2007-03-29ARENA PHARMA
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Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
ARENA PHARMA
Publication Date
2007-03-29
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates to certain fused aryl and heteroaryl derivatives of Formula (I) that are modulators of metabolism. Accordingly, compounds of the present invention are useful in the prophylaxis or treatment of metabolic disorders and complications thereof, such as, diabetes and obesity.
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Description

CROSS REFERENCE TO RELATED APPLICATIONS

[0001] This application is a continuation of U.S. Ser. No. 11 / 355,785, filed Feb. 16, 2006, which is a divisional of U.S. Ser. No. 10 / 890,549, now U.S. Pat. No. 7,132,426, filed Jul. 13,2004, which in turn claims the benefit of U.S. Provisional Applications Ser. Nos. 60 / 487,443, filed Jul. 14, 2003 and 60 / 510,644, filed Oct. 10, 2003, each of which is hereby incorporated by reference in its entirety.FIELD OF THE INVENTION

[0002] The present invention relates to certain fused aryl and heteroaryl derivatives that are modulators of glucose metabolism. Accordingly, compounds of the present invention are useful in the prophylaxis or treatment of metabolic disorders and complications thereof, such as, diabetes and obesity. BACKGROUND OF THE INVENTION

[0003] Diabetes mellitus is a serious disease afflicting over 100 million people worldwide. In the United States, there are more than 12 million diabetics, with 600,000 new cases diagnosed each year. [0...

Claims

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