Method of forming polymeric microarray support

a technology of microarrays and supports, applied in the field of forming polymeric microarray supports, can solve the problem of higher background signal from autofluorescence in comparison
US20110306519A1Inactive Publication Date: 2011-12-15AMIC AB (SE)
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Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
AMIC AB (SE)
Publication Date
2011-12-15
Estimated Expiration
Not applicable · inactive patent

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Abstract

In combination, a polymeric microarray support for an optical assay arrangement, that includes an optical detection instrument having a known depth of focus for detecting light emitted from said microarray support. The polymeric microarray support has a support surface made from a polymeric support material having a thickness varying over the area of the support surface by a thickness variation value. The said support includes formed microfeatures made up of grooves arranged to have a predetermined depth at the time of forming, the groove depth being selected based on the depth of focus of the optical detection instrument and the thickness of the support. The sum of the depth for the grooves and the thickness variation value of the polymeric support surface substantially corresponds to the depth of focus of the optical detection instrument in order to reduce noise, the polymeric support surface having attached thereto probe molecules to form binding sites.
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Description

CROSS REFERENCE TO RELATED APPLICATIONS

[0001] This application is a divisional application of U.S. Ser. No. 10 / 556,961, filed on Nov. 15, 2005, which is a U.S. National Stage application of International Application number PCT / SE2004 / 000761, filed May 18, 2004 under 35 U.S.C. §371, which claims priority to Swedish Application Serial No. SE 0301470-1, filed May 20, 2003, the entire contents of each noted document herein being incorporated by reference.TECHNICAL OF THE INVENTION

[0002] The present invention relates to an improved polymeric microarray support for an optical assay arrangement, the microarray support provided with microfeatures comprising a surface enlarging pattern. The invention also relates to an optical assay arrangement comprising an improved polymeric microarray support provided with microfeatures comprising a surface enlarging pattern, and to a method of forming microfeatures comprising a surface enlarging pattern in a polymeric microarray support for an optical assa...

Claims

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