56 results about "Hydroxyquinoline derivatives" patented technology

The invention relates to a preparation method of a fluorescence enhanced fluorescent molecular probe for detecting mercapto-containing amino acids, and an application of the probe, and concretely relates to a preparation method of a 7-hydroxyquinoline derivative and an application of the 7-hydroxyquinoline derivative in the mercaptoamino acid detection. The fluorescent probe is a pure probe synthesized through directly reacting the 7-hydroxyquinoline derivative with dimethyl sulfate. The largest absorption wavelength of the molecule of the probe is 315nm; and the absorption wavelength of the probe molecule redshifts to 406nm from 315nm with the addition of the mercapto-containing amino acids, the intensity of a fluorescent spectrum at 505nm is continuously enhanced, and very strong green fluorescence is emitted. The probe molecule has the advantages of high detection sensitivity, strong identification capability on the mercapto-containing amino acids, and fast response speed, and has detection limits of Cys, GSH and Hcy mercaptoamino acids being 23nM, 52nM and 5.3nM respectively, and like probes have important application values in the biochemical field and the like.