An input device with ghost key suppression includes a switch module, a comparator, an exchange unit, a bias voltage resistor, and a processing module. The switch module includes a plurality of strobe lines, a plurality of sense lines, and a plurality of switch units. Each of the switch units has a switch and a resistor connected in series between a corresponding one of the strobe lines and a corresponding one of the sense lines. The comparator is configured for comparing a signal received at an input end thereof with a reference signal for generating the comparison signal. The exchange unit is electrically connected to the sense lines and the comparator, and is operable in response to a control input for making and breaking electrical connection between each of the sense lines and the input end of the comparator. The processing module controls operation of the switch module and the exchange unit based on the comparison signal.