The utility model discloses an automatic weighing and packaging device for granules, which relates to the technical field of packaging devices and comprises a base and a slider. A fixed plate is arranged at the position, close to one side, of the top of the sliding block, a clamping screw rod is arranged at the bottom of the fixed plate in the direction facing the motor, the surface of the clamping screw rod is sleeved with a clamping plate, clamping blocks are arranged at the positions, facing the center of the sliding block, of the fixed plate and the movable plate, side frames are arranged on the front face and the back face of the sliding block, and transverse rod bases are transversely installed on the side frames in a penetrating mode; a cross rod is arranged between the cross rod seats; the sealing edges on the two sides of a packaging bag are clamped through the clamping blocks, an opening of the packaging bag is fixed upwards, the transverse bar is lifted to lift the packaging bag, the packaging bag can be fixed by adjusting the positions of the movable plate and the transverse bar of the clamping structure, the packaging bag fixing device can fix packaging bags of any size, and the application range of the packaging bag fixing device is wider.