The invention discloses a microcapsule and a preparation method thereof, and self-repairing
polyurethane and a preparation method and application thereof, relates to the field of
polyurethane materials, and solves the problems that the self-repairing process of the self-repairing
polyurethane in the prior art depends on non-physiological stimulation conditions, the
cytotoxicity is high, the
biosafety is insufficient, and the application requirements in the field of biomedical instruments are difficult to meet. The invention discloses a preparation method of self-repairing polyurethane, which comprises the following steps: blending a
prepolymer I, a
prepolymer II and a
solvent, adding an Arabic gum
aqueous solution and a chain
extender, and adding
triethanolamine to obtain a suspension containing microcapsules; and washing, carrying out
solid-liquid separation, and freeze-
drying to obtain the microcapsule. Adding the microcapsules into the polyurethane dioxane solution, uniformly stirring, pouring into a mold, and heating or freeze-
drying in vacuum to obtain the self-repairing polyurethane. The microcapsule provided by the invention has excellent
biocompatibility,
solvent resistance and mechanical properties, the self-repairing condition of the self-repairing polyurethane is mild, and the application requirements in the field of biomedical instruments are met.