Composition containing moutan root bark extract as active ingredient

A technology of the root bark and composition of Paeonia suffruticosa is applied in the field of compositions containing the extract of Paeonia suffruticosa root bark as an active ingredient, and can solve the problems of adhesion to clothing, excessive dosage, difficulty in controlling the amount of uniform coating, etc.

Inactive Publication Date: 2007-09-05
MICRO SCIENCE TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the case of applying the composition of this dosage form to the affected part, when the part to be applied is large, a large amount of drug is required, but it is difficult to control the amount of uniform application, and semi - Solids (e.g. ointments and creams) have problems sticking to clothing when applied to the skin
[0013] In addition, when an antibacterial agent or an antifungal agent is used for oral administration, the drug circulates throughout the body, so in order to obtain an effect from the drug, an excessive dose must be administered, and side effects due to long-term administration may occur
In particular, the toxicity of triazole-derived drugs in the body has become a problem: for example, when ingested for a long time, causing side effects in the liver

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-11

[0068] Example 1-11: Preparation of plant extracts

[0069] Buy the root bark of tree peony sold for medicinal purposes, that is, the root bark of Paeoniaceae (Peony). The peony root bark is completely dried and crushed, and then passed through a 1.18-mm sieve. 10 kg of each of the solvents listed in Table 1 below were separately added to 1 kg of pulverized tree peony root bark, and then left at room temperature for 8 hours. After that, it was extracted at 45°C for 12 hours, and then filtered with a Wattman#6 filter to obtain a filtrate. Under reduced pressure at 60°C, the filtrate was concentrated in a distillation apparatus with a condenser to obtain an extract.

[0070] The yield of the Paeonia suffruticosa root bark extract of each solvent is shown in Table 1 below.

[0071] Solvent

[0072] Experiment 1

[0073] 1. Patch test

[0074] The skin irritation of peony root bark extract was studied by patch test.

[0075] Each plant e...

Embodiment 12-16

[0093] Example 12-16: Preparation of Liquid Sterilizer

[0094] The sterilizing and disinfecting composition containing the peony root bark and natural herbal substances of Examples 1-11 can produce the function of masking the odor, which is mixed with purified water and ethanol, and prepared as shown in Table 4 below (unit: wt%).

[0095] The bactericidal ability was measured according to the strain reduction rate measurement method (shaking flask method), in which observations began with inoculation of Escherichia coli (KCTC 1682), Staphylococcus aureus (KCTC1621), and Salmonella typhimurium (KCTC 1925) 24 The reduction rate of bacteria after hours, these strains are easy to find in daily life, and the results are shown in Table 4 below.

[0096] Composition ingredients

[0097] It can be seen from Table 4 above that the peony root bark extract of the present invention still maintains excellent antibacterial activity, even when they are liquids and solutions...

Embodiment 17-21

[0099] Prepare antibacterial agents according to the combination ratio in Table 5 below, and verify their antibacterial activity.

[0100] Example

[0101] It can be seen from Table 5 above that the antibacterial agent containing the ethyl acetate extract of peony root bark and the antibacterial compound has excellent antibacterial and antifungal activity.

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PUM

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Abstract

The present invention relates to a composition comprising a Moutan root bark extract as an active ingredient, and particularly to a composition for the prevention and treatment of athlete's foot, osmidrosis, or acne; a composition for oral cleansing; a bactericidal / disinfectant composition; a composition for eliminating dandruff-causing pathogens and controlling odor, and a functional kitchen detergent composition. The compositions comprising the Moutan root bark extract as an active ingredient of the present invention have superior bactericidal effects against bacteria including athlete's foot-causing pathogens, skin eczema-causing pathogens and skin flora, and fungi, and they can be easily and simply applied to medicines, cosmetics, or cleansing agents.

Description

Background of the invention [0001] (a) Technical field [0002] The present invention relates to a composition containing tree peony root bark extract as an active ingredient, and more specifically, to a composition for preventing and treating athlete's foot, underarm odor, or acne, and a composition for oral cleaning , A bactericidal / disinfectant composition, and a kitchen detergent composition, which can be applied to medicines, cosmetics or detergents. [0003] (b) Description of related technologies [0004] Bacteria or fungi exist all over the world, and there are many kinds of them. Bacteria and fungi grow and multiply under suitable growth conditions, and they can induce diseases in animals including humans. Specifically, candidiasis and athlete's foot frequently occur due to fungi, and microorganisms can cause damage to the quality and properties of food or industrial products. [0005] Fungi live in the skin and cause skin-mycosis. In particular, dermatophytes parasitizin...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/71A61K8/02A61Q99/00A61K125/00A61K9/12A61K8/00A61K8/30A61K8/31A61K8/34A61K8/37A61K8/39A61K8/40A61K8/41A61K8/49A61K8/55A61K8/58A61K8/60A61K8/63A61K8/72A61K8/73A61K8/86A61K8/92A61K8/96A61K8/97A61K8/98A61K31/137A61K31/343A61K31/4164A61K31/4174A61K31/4196A61K31/496A61K31/505A61K31/7048A61K36/18A61K36/65A61K47/10A61K47/14A61K47/18A61K47/22A61K47/24A61K47/28A61K47/34A61K47/36A61K47/40A61K47/44A61P31/10A61Q5/00A61Q11/00A61Q15/00A61Q19/00A61Q19/10A61Q90/00
CPCA61K8/97A61Q15/00A61Q17/005A61Q5/006A61K31/496A61Q11/00A61K36/65A61K8/9728A61K8/9761A61K8/9789A61K8/9767A61P31/10Y02A50/30A61K2300/00
Inventor 文雄植金载哲姜欣濉孙圣民
Owner MICRO SCIENCE TECH CO LTD
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