Anti-sticking flush fluid

Abstract

The invention relates to an anti-adhesive surgery washing liquid, which comprises that using acid sodium phosphate and sodium acid phosphate as buffer couple, using 0.01-5% carboxymethyl chitose, 0.01-1% sodium chloride, 0-1% acid sodium phosphate, 0-1% sodium acid phosphate, and the left is water. The motion viscosity of invention is 0.1-20mm2 / s, while its pH value is 6-8. The invention has low cost and simple operation, while it can restrain bacterial, accelerate healing, stop blooding, or the like, with wide application in surgery.

Description

technical field [0001] The invention relates to a medical device, in particular to an anti-adhesion operation flushing liquid. Background technique [0002] Intraoperative flushing is a routine surgical operation to maintain a good aseptic condition and surgical field of view, and at the same time remove tissue fragments and exuded blood produced during the operation in a timely manner. Currently, the commonly used flushing fluid in surgical operations is mainly saline. There are also a small number of hospitals that use functional flushing solutions with antibacterial and anti-inflammatory effects (such as metronidazole surgical flushing solutions, etc.). [0003] After the implementation of obstetrics and gynecology, abdominal surgery, cardiothoracic surgery and orthopedic surgery, most patients generally have adhesion problems in the postoperative healing process. According to statistics, the annual cost of treating abdominal and pelvic adhesions in the United States is a...

AI Technical Summary

Problems solved by technology

Adhesions are abnormal structures formed by ligaments of connective tissue joining adjacent tissues or organs. The complexity can range from a thin film to dense vascular scar tissue. The causes of adhesions include surgical trauma, ischemia, Existence of foreign matter, bleeding and exposure of the wound surface and bacterial infection, the current methods of preventing adhesions include: improving surgical operations, drug therapy, biological therapy and the use of spacers, etc. The method of improving surgical techniques is to reduce adhesions to a certain extent However, judging from the reasons for the formation of adhesions, it cannot effectively prevent adhesions; and due to the lack of effective drug carriers for systemic administration, it cannot reach the adhesion site very effectively, and the rapid absorption of the peritoneum limits the half-life of the drug. Drug anti-adhesion has not yet been generally recognized clinically; in the early days, non-degradable macromolecules were used as membrane materials, which increased the suffering of patients due to the need for secondary surgery to remove them. Macromolecular substances such as regenerated cellulose are used as membrane materials. Due to the fact that the above materials cannot be biodegraded in the body, or have a short storage time and lack of safety, animal experiments and clinical applications have not been unanimously approved; and these anti-adhesion methods Or products that only focus on reducing the severity and scope of adhesions, have no anti-inflammatory and protective effects on tissue wound surfaces, and are helpless against postoperative tissue fluid inflammatory exudation, causing tissue wound inflammation and adhesions

Therefore, these conventional anti-adhesion methods or products have their own advantages and disadvantages