Externally applied aceclofenac gel prepn and its prepn process

Abstract

The present invention discloses one kind of externally applied aceclofenac gel preparation and its preparation process. The externally applied aceclofenac gel preparation is compounded with aceclofenac 0.5-8 wt%, organic solvent 5-50 wt%, bacteriostat 0.001-10 wt%, pH regulator 0.01-2 wt%, carbomer 0.5-8 wt%, antioxidant 0.01-5 wt% and water for the rest. It is prepared through mixing the said ingredients. It is applied to the joint or other disease focus to result in obvious curative effect.

Description

technical field

[0001] The invention relates to medicines, in particular to aceclofenac gel for external use and a preparation method thereof. Background technique

[0002] Aceclofenac is a phenylacetic acid non-steroidal anti-inflammatory analgesic, the chemical name is: 2-[(2,6-dichlorophenyl) amino] phenylacetoxyacetic acid, listed in Spain in 1992, the dosage form is 100mg tablet, orally twice a day, 100mg each time, mainly treats the induced stage of degenerative joint disease, chronic arthritis, chronic migratory arthritis, chronic ankylosing back spondylitis and pain caused by various inflammations such as Low back pain, toothache and other diseases, although aceclofenac has the characteristics of safe medication and good curative effect, but it will cause some discomfort to the stomach after oral administration, and sometimes symptoms such as dizziness and elevated liver enzymes. Therefore, in recent years, Some scientific research institutions such as South Korea h...

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