Granisetron hydrochloride orally disintegrating tablets

A technology of granisetron hydrochloride and orally disintegrating tablets, which is applied in the direction of pill delivery, digestive system, drug combination, etc., can solve the problems of incomplete dispersion, disintegration of orally disintegrating tablets, poor tablet hardness and integrity, and achieve High dissolution rate, overcoming disintegration, fast disintegration and dispersion
CN101095679AInactive Publication Date: 2008-01-02HONGYI SCI & TECH CO LTD NANCHANG

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
HONGYI SCI & TECH CO LTD NANCHANG
Publication Date
2008-01-02
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to granisetron hydrochloride mouth slaking tablet and the formula and preparing process. The process employs rotary oscillating granulator to produce said slaking agent through direct sheeting method after heat extrusion by melting and gradient cooling. When compared with mouth slaking agent produced with normal melting method, the mouth slaking agent in this invention is characterized by faster slaking speed, higher dissolution rate, intact tablet outlook, stronger rigidity and good taste. If compared with current freeze drying, vacuum drying, spray drying technique, the invention is characterized in that it needs no special production device and condition, no special package, the production process is simple, quality is stable and suitable for industrial production. It provides new products for patients that is dysphagia and bedridden, for old people and children, especially for patients suffering tumor chemotherapy and radiotheraphy.
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Description

technical field

[0001] The invention relates to a granisetron hydrochloride orally disintegrating tablet and a prescription and a process for preparing the granisetron hydrochloride orally disintegrating tablet through a rotary swinging granulator granulation direct tableting method after gradient cooling by melting and hot extrusion. Background technique

[0002] Tumor has become the first enemy that threatens human life and health. According to a research report released by the International Cancer Research Center of the World Health Organization in May 2003, according to the current trend of cancer incidence, the incidence of cancer in the world in 2002 increased by 50% compared with the past, and the number of new cancer patients in the world will reach 1500 every year. million people. According to the research report of the center, the cancer with the highest incidence rate in the world is lung cancer, with 1.2 million new patients every year; breast cancer, with about...

Claims

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