Method for preparing complex nanometer fibrous tissue renovation bracket containing collagen
A technology of composite nanofibers and collagen, which is applied in the field of preparation of composite nanofiber tissue repair scaffolds, can solve the problems that have not been reported, cannot meet the requirements of mechanical properties of tissue repair materials, and the mechanical properties of materials are low, and achieve good biological Compatibility, excellent mechanical properties, effects of high porosity
Inactive Publication Date: 2008-04-09
DONGHUA UNIV
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The invention relates to a preparation method of a composite nanofiber tissue repair scaffold which contains collagen. The steps are as follows: firstly, collogen spinning solution is prepared; secondly, thermosplastic polyurethane spinning solution is prepared; thirdly, the collogen spinning solution and the thermosplastic polyurethane spinning solution are mixed according to the proportion and agitated to be even, and then static spinning solution is obtained; fourthly, the static spinning solution is arranged in a static spinning device, the spinning industry parameter is adjusted, the mold shape of a receiving device is changed, and then static spinning composite nanofiber tissue repair scaffolds with different shapes are obtained. The scaffold with the material has good biological compatibility and mechanical property, and higher void factor, and the scaffold is hopeful to be used as the repair scaffold materials of the tissues such as blood vessel, nerve, valve, etc.
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Property | Measurement | Unit |
Average fiber diameter | 345.0 | nm |
Average fiber diameter | 208.0 | nm |
Thickness | 0.08 | nm |
tensile | MPa | |
Particle size | Pa | |
strength | 10 |
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