Method for preparing complex nanometer fibrous tissue renovation bracket containing collagen
A technology of composite nanofibers and collagen, which is applied in the field of preparation of composite nanofiber tissue repair scaffolds, can solve the problems that have not been reported, cannot meet the requirements of mechanical properties of tissue repair materials, and the mechanical properties of materials are low, and achieve good biological Compatibility, excellent mechanical properties, effects of high porosity
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Example Embodiment
[0020] Example 1
[0021] Use an electronic analytical balance to weigh 0.3g of collagen and dissolve it in 5ml of hexafluoroisopropanol, stir with micro-thermal magnetic force until it is completely dissolved, and obtain a collagen spinning solution with a concentration of 6% (g / ml); use an electronic analytical balance to weigh Dissolve 0.3g of thermoplastic polyurethane in 5ml of hexafluoroisopropanol, stir with micro-thermal magnetic force until it is completely dissolved, and obtain a thermoplastic polyurethane spinning solution with a concentration of 6% (g / ml); after the two are completely dissolved, press the two The ratio of 2:8 is evenly mixed, and the total concentration of the mixed solution is 6%; the electrospinning process is: spinning voltage is 12kv, syringe pump advancement speed is 1.5ml / h, receiving distance is 12cm, using 9 gauge needle, aluminum foil accepting Or degreased gauze accepts fibers to obtain a disordered nanofiber film with an average fiber diamet...
Example Embodiment
[0022] Example 2
[0023] Use an electronic analytical balance to weigh 0.3g of collagen and dissolve it in 5ml of hexafluoroisopropanol, stir with micro-thermal magnetic force until it is completely dissolved, and obtain a collagen spinning solution with a concentration of 6% (g / ml); use an electronic analytical balance to weigh Dissolve 0.3g of thermoplastic polyurethane in 5ml of hexafluoroisopropanol, stir with micro-thermal magnetic force until it is completely dissolved, and obtain a thermoplastic polyurethane spinning solution with a concentration of 6% (g / ml); after the two are completely dissolved, press the two The ratio of 6:4 is mixed evenly, and the total concentration of the mixed solution is 6%; the electrospinning process is: spinning voltage is 16kv, syringe pump advancement speed is 1.2ml / h, receiving distance is 12cm, using 9 gauge needle, aluminum foil accepting Or degreased gauze accepts fibers to obtain a disordered nanofiber film with an average fiber diamet...
Example Embodiment
[0024] Example 3
[0025] Use an electronic analytical balance to weigh 0.4g of collagen and dissolve it in 5ml of hexafluoroisopropanol, stir with micro-thermal magnetic force until it is completely dissolved, and obtain a collagen spinning solution with a concentration of 8% (g / ml); use an electronic analytical balance to weigh Dissolve 0.5g of thermoplastic polyurethane in 10ml of hexafluoroisopropanol, stir it with micro-thermal magnetic force until it is completely dissolved, and obtain a thermoplastic polyurethane spinning solution with a concentration of 5% (g / ml); after the two are completely dissolved, the volume of both The ratio of 5:8 is mixed evenly, and the total concentration of the mixed solution is 6.2%; the electrospinning process is: spinning voltage is 16kv, syringe pump advancement speed is 1.2ml / h, receiving distance is 12cm, and No. 9 needle is selected. The aluminum foil accepts or the degreased gauze accepts the fibers to obtain a disordered nanofiber film...
PUM
Property | Measurement | Unit |
---|---|---|
Average fiber diameter | aaaaa | aaaaa |
Average fiber diameter | aaaaa | aaaaa |
Thickness | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap