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Medicine compounds for treating primary trigeminal neuralgia and preparing method thereof

A technology of trigeminal neuralgia and its composition, which is applied in the field of traditional Chinese medicine preparation, can solve the problems of postoperative recurrence and sequelae, damage to the trigeminal nerve, and high recurrence rate, and achieve the effects of no toxic side effects, good curative effect, and less recurrence

Inactive Publication Date: 2008-07-23
BEIJING ZHONGKE YONGHE PHARMA TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above methods are all for destroying the trigeminal nerve, so that the trigeminal nerve loses its normal physiological function to achieve temporary pain relief, which can cause sequelae such as facial paralysis, hemiplegia, ataxia, etc. After a period of time, the trigeminal nerve regenerates, causing pain again, and the recurrence rate is high.
(6) X-knife and Gamma Knife treatment, burn off the nerve by rays, the cost is high, and it will also cause postoperative recurrence and sequelae

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment 2

[0053] Piper longum 15kg Gujingcao 23kg Angelica dahurica 15kg Chuanxiong 23kg Gastrodia elata 23kg

[0054] Uncaria 23kg, Silkworm 15kg, Scorpion 9kg, Centipede 15kg, Paeoniae Alba 23kg

[0055] Licorice 15kg Bupleurum 15kg

[0056] Grind the scorpion into a fine powder for later use, crush Uncaria into a coarse powder, heat and reflux extraction with 6 times the amount of 60-80% ethanol for 3 times, each time for 1.5 hours, combine the extracts, filter, recover the ethanol, and concentrate to a relative density of 1.30-1.35 extract (heated at 50-60°C), vacuum-dried, crushed and sieved through an 80-mesh sieve, and set aside; the other ten traditional Chinese medicines such as longum longum were decocted with 8-10 times the amount of water for three times, followed by 2 hours and 1.5 hours , 1 hour, filtered, the filtrate was concentrated to a relative density of 1.15 ~ 1.20 extract (50 ~ 60 ℃ heat test); add scorpion powder and Uncaria extract, dry. Crush into fine powder,...

specific Embodiment 3

[0057] Piper longum 10kg Gujingcao 15kg Angelica dahurica 10kg Chuanxiong 15kg Gastrodia elata 15kg

[0058] Uncaria 15kg, Silkworm 10kg, Scorpion 6kg, Centipede 6kg, Paeoniae Alba 15kg, Gan

[0059] Grass 10kg Bupleurum 10kg

[0060] Grind the scorpion into a fine powder for later use, crush Uncaria into a coarse powder, heat and reflux extraction with 6 times the amount of 60-80% ethanol for 3 times, each time for 1.5 hours, combine the extracts, filter, recover the ethanol, and concentrate to a relative density of 1.30-1.35 extract (heated at 50-60°C), vacuum-dried, crushed and sieved through an 80-mesh sieve, and set aside; the other ten traditional Chinese medicines such as longum longum were decocted with 8-10 times the amount of water for three times, followed by 2 hours and 1.5 hours , 1 hour, filtered, the filtrate was concentrated to a relative density of 1.15 ~ 1.20 extract (50 ~ 60 ℃ heat test); add scorpion powder and Uncaria extract, dry. Crush into fine powder...

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PUM

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Abstract

The invention discloses a medicine combination for treating primary trigeminal neuralgia and is prepared by twelve traditional Chinese medicines of piper longum, pipewort, root of dahuriae angelica, hemlock parsley, rhizoma gastrodiae, gambir plant, stiff silkworm, scorpion, centipede, white paeony root, liquorice and radix bupleuri. The medicine combination of the invention has the functions of dispersing wind, clearing collateral and easing pain, and can be used for treating primary trigeminal neuralgia. The invention has rapid effect, good curative effect, simple preparation, high application value but no toxic and side effect. .

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparation, and specifically relates to a traditional Chinese medicine preparation for treating primary trigeminal neuralgia and a preparation method thereof. Background technique [0002] Trigeminal neuralgia is a recurrent severe pain in the distribution area of ​​the trigeminal nerve in the face. Trigeminal neuralgia is the most common neurological pain disease, mostly occurs in middle-aged and elderly people, and more women than men. At the onset of the disease, short-term paroxysmal lightning-like pain suddenly appeared in the distribution area of ​​the trigeminal nerve in the patient's face for no reason. The trend of pain attacks is mostly mild at first, with fewer pain attacks and longer intervals, and there may be a considerable period of remission, which can last for weeks, months, or even years. With the development of the disease in most patients, the pain attac...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61P25/04A61K35/64
Inventor 程华鄢良张韬
Owner BEIJING ZHONGKE YONGHE PHARMA TECH
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